缺血性卒中患者颅内外动脉狭窄的相关性研究  

Study on the correlation between intracranial and extracranial artery stenosis in patients with ischemic stroke

作　　者：邓杰尹 秦杨[1] 刘松涛 李改丽[1] 

机构地区：[1]成都军区总医院老年科,610083 [2]新津县兴义中心卫生院内科

出　　处：《中国综合临床》2017年第10期904-906,共3页Clinical Medicine of China

摘　　要：目的 明确缺血性脑卒中患者颅内外动脉狭窄是否存在相关性,并了解二者主要危险因素的差异.方法 收集我院2014年7月至2016年5月收治的168例症状性缺血性卒中患者的临床资料,分析颅内动脉狭窄与颅外动脉狭窄的相关性及危险因素差异.结果 168例患者中存在动脉异常（含内膜增厚）者123例（73.2%）;动脉狭窄者100例（59.5%）,含颅内动脉狭窄33例,颅外动脉狭窄48例,颅内外同狭窄19例;颅外动脉狭窄率（39.9%）比颅内动脉狭窄率（31.0%）高,但两者比较差异无统计学意义（χ2=2.93,P=0.11）,两者间无明确相关性（χ2=0.35;P=0.61）,颅内、外动脉狭窄患者年龄、平均动脉压比较差异均有统计学意义（t=1.98,P=0.05;t=5.42,P〈0.001）,但性别及血压、血糖、血脂异常率比较差异均无统计学意义（χ2值分别为1.15、3.41、0.43、0.81,P均〉0.05）.结论 颅外动脉狭窄可能无法预测颅内动脉狭窄的可能性,颅外动脉狭窄可能更易引起缺血性脑卒.Objective To determine whether there is correlation between intracranial and extracranial arterial stenosis in patients with ischemic stroke,and to understand the difference of the main risk factors between them.Methods One hundred and sixty-eight patients with symptomatic ischemic stroke were selected in order to analyze the correlation and risk factors of intracranial arterial stenosis and extracranial arterial stenosis.Results In the 168 cases,123 patients（73.2%）were with abnormal artery（include intimal thickening）and 100 patients（59.5%）were diagnosed with artery stenosis,including 33 cases of intracranial artery stenosis,48 cases of extracranial artery stenosis and 19 cases of intracranial and extracranial stenosis.The rate of extracranial artery stenosis（39.9%）was higher than that of intracranial artery stenosis（31.0%）,but there was no significant difference between them（χ2 =2.93,P=0.11）.There was no definite correlation between them（χ2 =0.35,P=0.61）and there were statistically significant differences in age and arterial pressure between patients with intracranial and mean extracranial artery stenosis（t=1.98,P=0.05;t=5.42,P〈0.001）,but the gender,blood pressure,blood glucose and dyslipidemia rate showed no significant difference （χ2 =1.15,3.41,0.43,0.81,P〉0.05）.Conclusion Extracranial arterial stenosis may not predict the possibility of intracranial arterial stenosis,and extracranial arterial stenosis may be more likely to cause ischemic stroke.

关 键 词：缺血性卒中 颅内动脉狭窄 颅外动脉狭窄 CT血管成像 超声检查 

分 类 号：R743.3[医药卫生—神经病学与精神病学]