白化金黄仓鼠血液生理指标测定  

Detection of Blood Physiological Parameters in Albino Mutant Golden Hamster

作　　者：崔晓霞 尚世臣 马兰芝 黄斌 尚玉璞 王冬平 陈振文[2] 王全新 

机构地区：[1]军事科学院军事医学研究院实验动物中心,北京100071 [2]首都医科大学实验动物科学部,北京100069 [3]辽宁长生生物技术有限公司,本溪117004

出　　处：《实验动物与比较医学》2017年第6期478-481,487,共5页Laboratory Animal and Comparative Medicine

基　　金：国家自然科学基金项目(No.3137227)

摘　　要：目的测定白化金黄仓鼠的血液生理指标,并与野生型金黄仓鼠进行比较。方法用眶静脉丛采血的方法采集白化及野生型金黄仓鼠全血,制备抗凝血,应用全自动血细胞分析仪及半自动血液凝固分析仪进行测定,应用SPSS17.0软件包对结果进行统计分析。结果初步测定了白化突变及野生型金黄仓鼠的血液生理指标,二者的部分指标存在差异。结论金黄仓鼠的白化基因突变可能对血液生理指标有一定影响。Objective To detect the normal range of blood physiological parameters in albino mutant golden hamster and compared with wild type golden hamster. Methods Blood samples were taken from orbital venous plexus of hamsters. A number of blood physiological parameters were measured using automatic blood cell analyzer and semi-automatic coagulometer. The data was analyzed with SPSS 17.0. Results The range of normal values of blood physiological data of albino mutant golden hamster and golden hamster were detected. There were significant differences between albino mutant golden hamster and golden hamster in some indexes. Conclusion The albino mutant in golden hamster may be influ- ence the normal values of some blood physiological indexes.

关 键 词：白化突变 金黄仓鼠 血液生理指标 

分 类 号：R-332[医药卫生]