枳实消痞汤治疗功能性消化不良Meta分析  

Meta-analysis of Zhishi Xiaopi Decoction in Treating Functional Dyspepsia

作　　者：苏洪佳 陈国忠[2] 谢君艳 黄丽萍[1] 谢卓恩 

机构地区：[1]广西中医药大学,广西南宁530001 [2]广西中医药大学第一附属医院,广西南宁530023

出　　处：《辽宁中医药大学学报》2018年第1期147-150,共4页Journal of Liaoning University of Traditional Chinese Medicine

基　　金：国家自然科学基金资助项目(81560758,81260529)

摘　　要：目的 ：评价枳实消痞汤治疗功能性消化不良（FD）的临床疗效。方法 ：计算机检索维普数据库（VIP）、万方数据库、中国期刊全文数据库（CNKI）,纳入有关枳实消痞汤治疗功能性消化不良的临床随机对照研究,按照RCT质量评价的修改后Jadad量表评价标准对纳入文献进行质量评价,使用Review Manger 5.3软件进行Meta分析统计学处理。结果 ：共纳入16个RCT研究,包括1348例患者。Meta分析结果显示：与对照组相比,枳实消痞汤治疗FD在临床总有效率、治愈率、上腹痛、腹胀及早饱等主要临床症状改善情况均显示出较好的疗效。结论 ：研究表明,枳实消痞汤治疗功能性消化不良有较好疗效,但还需大样本、高质量的随机对照试验进一步验证支持。Objective ：To assess the efficacy of Zhishi Xiaopi Decoction on the treatment of functional dyspepsia（FD）. Methods ：According to strict inclusive and exclusive criteria,through electronic searches of relevant randomized controlled trials（RCTs）on Zhishi Xiaopi Decoction for FD in VIP Database,Wan Fang Data and CNKI. All reviewed literatures were assessed via Jadad quality scale. Data statistical analyses were performed by Rev Man 5.3. Results ：16 trials involving 1348 patients were included. Metaanalysis showed that compared with the control group,Zhishi Xiaopi Decoction for the FD treatment group had superiority in many aspects such as effective rate according to clinical efficient,recovery rate,upper abdominal pain,abdominal distension and early full and so on. Conclusion ：Zhishi Xiaopi Decoction treatment for FD shows curative effect,but still need large sample,more high quality studies to prove this view point.

关 键 词：功能性消化不良 枳实消痞汤 随机对照试验 META分析 

分 类 号：R57[医药卫生—消化系统]