佛山地区急性脑出血中医证型与hs-CRP和IL-1的相关性研究  

Study on correlativity between TCM syndrome and hs-CRP,IL-1 of acute intracerebral hemorrhage in Foshan area

作　　者：魏华[1] 黄金秀 蔡海荣[1] 李旷怡[1] 张英俭[1] 冯锦昉[1] 刘维政[1] 黎练达[1] 

机构地区：[1]广东省佛山市中医院 [2]广东省佛山市第一人民医院

出　　处：《山西中医》2018年第1期46-48,共3页Shanxi Journal of Traditional Chinese Medicine

基　　金：广东省佛山市重点专科培育建设项目(编号:Fspy2-2015004);广东省佛山市十三五高水平重点专科建设项目(编号:FSGSPZD135025);广东省佛山市急性脑率中一体化综合救治平台建设(编号:2014AG10002)

摘　　要：目的:探讨急性脑出血患者中医证型与血清hs-CRP和IL-1的相关性。方法:纳入急性脑出血患者320例,判定中医证型并检测血清hs-CRP、IL-1的水平。结果:急性脑出血患者中医证型分布从高到低依次为痰热腑实证(26.88%)、风痰火亢证(19.69%)、风痰瘀阻证(16.88%)、痰湿蒙神证(11.25%)、风火上亢证(9.38%)、气虚血瘀证(8.44%)和阴虚风动证(7.50%);风火上扰证、风痰火亢证和痰热腑实证的hs-CRP和IL-1水平明显高于其余4种证型(P<0.05)。结论:急性脑出血中医证型分布具有一定的规律,不同中医证型间血清hs-CRP和IL-1水平存在差异。Objective: To approach the correlativity between TCM syndrome and serum hs-CRP,IL-1 in patients with acute intracerebral hemorrhage. Methods: 320 patients with acute intracerebral hemorrhage were inclued. TCM syndromes were judged,and the levels of serum hs-CRP and IL-1 were detected. Results: The distribution of TCM syndromes of patients with acute intracerebral hemorrhage was in the order from high to low,as follows: syndrome of phlegm-heat and Fu-excess( 26. 88%),syndrome of wind-phlegm and fire hyperactivity( 19. 69%),syndrome of wind-phlegm and blood stasis( 16. 88%),syndrome of phlegm-dampness and clouding orifices( 11. 25%),syndrome of wind-fire hyperactivity( 9. 38%),syndrome of qi deficiency and blood stasis( 8. 44%),syndrome of stirring wind due to yin deficiency( 7. 50%). The levels of hs-CRP and IL-1 of wind-fire hyperactivity syndrome,wind-phlegm and fire hyperactivity syndrome and phlegm-heat and Fu-excess syndrome were significantly higher than other four syndromes( P < 0. 05). Conclusions: In the distribution of TCM syndromes of acute intracerebral hemorrhage,there is a certain regularity. Among different TCM syndrome types,the levels of serum hs-CRP and IL-1 exist the differences.

关 键 词：急性脑出血 中医证型 超敏C反应蛋白 白细胞介素-1 

分 类 号：R743.34[医药卫生—神经病学与精神病学]