320排容积CT全肿瘤灌注测量与常规轴位最大层面测量对肝细胞癌诊断价值的对比分析  

Comparison of total tumor perfusion and maximum diameter measurement in evaluating CT scan imaging in patients with hepatocellular carcinoma

作　　者：梁长华[1] 毛华杰[1] 岳军艳[1] 张会杰[1] 王东东[1] 户彦龙[1] 窦文广[1] 高剑波 

机构地区：[1]新乡医学院第一附属医院,河南省卫辉市453100 [2]郑州大学第一附属医院

出　　处：《实用肝脏病杂志》2018年第1期88-91,共4页Journal of Practical Hepatology

基　　金：河南省医学科技攻关项目-省部共建项目(编号:201701012)

摘　　要：目的比较全肿瘤灌注测量与轴位最大层面测量320排容积CT灌注成像诊断肝细胞癌的优缺点。方法56例肝细胞癌患者接受320排容积CT灌注成像检查,采用全肿瘤灌注和肿瘤轴位最大层面灌注测量肿瘤、瘤旁肝组织和正常肝组织的肝动脉灌注量(HAP)、门静脉灌注量(PVP)和肝动脉灌注指数(HAPI)。结果瘤体各灌注参数与瘤周肝组织或正常肝组织比,差异均有显著统计学意义(P<0.05);全肿瘤灌注测量值与轴位最大层面测量法得到的各参数均无统计学差异(P>0.05);两名医生应用两种方法测量获得的三种组织测量值无显著性统计学差异(P>0.05)。结论使用320排容积CT灌注成像检查肝细胞癌瘤体,应用轴位最大层面法测量可以获得同样的测量值,但减轻了工作量。Objective To compare the diagnosis of total tumor perfusion and maximum diameter measurement in assessing CT scan imaging in patients with hepatoeellular carcinoma （HCC）. Methods Fifty-six patients with hepatocellular carcinoma between January 2013 and January 2016 were recruited in this study. The 320 row volume CT perfusion imaging was performed. The parameters of hepatic peffusion were calculated, including hepatic artery perfusion （HAP）,portal vein peffusion （PVP） and hepatic peffusion index （HAPI）. The total tumor perfusion and the maximum diameter of tumors were applied to record the parameters of tumoral, peritumoral and normal liver tissues. Results The HAP and HAPI of tumors were much higher,while the PVP of tumors were much lower than those in peritumoral or normal liver tissue by both measurements （P〈0.05）;there was no significant difference between parameters of tumors by both measurements （P〉0.05）,and there was also no significant difference between parameters by two doctors who measure the parameters （P〉0.05）. Conclusion Tile total tumor perfusion or maximum diameter measurement in assessing CT scan imaging in patients with hepatocellular carcinoma is good,but the latter might be convenient and simple.

关 键 词：肝细胞癌 X线计算机体层摄影术 肿瘤灌注 轴位最大层面法测量 

分 类 号：R730.44[医药卫生—肿瘤] R735.7[医药卫生—临床医学]