大网膜原发性骨外软骨瘤1例并文献复习  

Primary extraskeletal chondroma of the greater omentum : Case report and review of literature

作　　者：赵海燕[1] 刘腾飞[2] 郑朝晖[1] 黄冠[1] 刘巍[1] 林文松[1] 朱正[1] 

机构地区：[1]深圳市龙岗中心医院病理科,广东深圳518116 [2]南方医科大学病理学系/南方医院病理科,广东广州510515

出　　处：《现代肿瘤医学》2018年第3期456-458,共3页Journal of Modern Oncology

摘　　要：目的:探讨大网膜原发性骨外软骨瘤的临床病理特征、鉴别诊断、治疗及预后。方法:分析一例33岁女性患者的临床资料,对病理标本进行常规HE染色和免疫组化染色,对染色结果进行分析判读,并检索国内外文献进行复习。结果:超声及CT均提示患者腹腔有包块;大体标本检查肿瘤组织部分呈分叶状,界清、质硬、灰白,周边见部分网膜组织;组织病理检查肿瘤由成熟透明软骨构成,呈小叶状排列,细胞无异型性;免疫组化检测肿瘤组织S-100阳性,Ki67阳性指数<1%;随访患者3年无复发或转移,各项结果共同支持大网膜原发性骨外软骨瘤的诊断,临床治疗方法首选完整切除。结论:大网膜原发性软骨瘤极其罕见,其发病机制尚不明确,治疗以手术完整切除为主。Objective：To explore the clinicopathological characteristics,differential diagnosis,treatment and prognosis in primary extraskeletal chondroma of the greater omentum.Methods：The clinical data of a 33-year-old woman was analyzed.Hematoxylin-eosin staining and immunohistochemistry were performed and the results were analyzed.In addition,we reviewed the domestic and international literature.Results：Ultrasound and computed tomography showed a mass in the abdomen of patient.Grossly,the tumor was lobulated,well-circumscribed,hard and gray.Around the tumor,there was a part of greater omentum.Histopathologically,the tumor was composed of mature hyaline cartilage,and arranged like lobular.The cells were not atypical.Immunohistochemically,S-100 was positive and Ki67 index was below 1%.The patient was doing very well with no complaints or metastasis after 2 years.All of the features were in accordance with the primary extraskeletal chondroma of the greater omentum.Resection was considered as the recommended therapy.Conclusion：The primary extraskeletal chondroma of the greater omentum is very rare,and the etiology is unknown.The therapy should be chosed is surgical resection.

关 键 词：大网膜 骨外软骨瘤 治疗 

分 类 号：R738.3[医药卫生—肿瘤]