分子印迹技术在分析化学中的应用进展  

Progress of molecular imprinting technique in analytical chemistry

作　　者：张文进[1] 王正雷[1] 孙志华[2] 

机构地区：[1]解放军第211医院,黑龙江哈尔滨150080 [2]黑龙江中医药大学附属第二医院,黑龙江哈尔滨150001

出　　处：《化学工程师》2017年第12期58-61,共4页Chemical Engineer

基　　金：黑龙江省科技攻关计划项目(G96CL9901);黑龙江省青年科学基金项目(H2017060)

摘　　要：在本篇文章中提到的分子印迹技术在化学应用中不仅具有较强的专一性同时还具有较高的选择性,其功能的实现主要依靠于有效单体与模板分子在技术过程中的选择、聚集与相关分子的洗脱。现阶段制备分子印迹聚合物的方法有很多,主要包括共价法、非共价法、包埋法等。该技术已逐渐被运用到各个领域如用于色谱分析、分离或富集金属离子、筛选有效的中药成分等。从分子所在的水平与角度增强对分子印迹的认识并努力探索新的方法,可以满足技术过程中水相与极性溶剂使用的要求,使分子印迹技术可以运用到更多的领域。Mentioned in this article in chemical application of molecular imprinting technology not only has strong specificity and has high selectivity, its function is heavily reliant on effective monomer and the implementa- tion of the template molecules in the process of technology selection, together with related molecules elution. At present, there are many methods for preparing molecularly imprinted polymers, including covalent method, non- covalent method, embedding method and so on. The technology has been gradually applied to various fields such as chromatography, separation or enrichment of metal ions, and screening effective Chinese medicinal ingredients. From the perspective of in molecular level and enhance the understanding of molecular imprinting and trying to ex- plore a new method, can satisfy the requirements of technical process polar solvent with water use, the molecular imprinting technology can be applied to more fields.

关 键 词：分子印迹技术 分子印迹聚合物 分析化学 色谱分离 同相萃取 

分 类 号：O652.7[理学—分析化学]