丙二腈在有机合成中的应用研究进展  

Application of Malononitrile in Organic Synthesis

作　　者：王翔[1] 秦晓燕[1] 杜东东[1] 谢佳敏 仝娜 陈平[1] 

机构地区：[1]淮阴师范学院化学化工学院,江苏淮安223300

出　　处：《广州化工》2018年第1期9-11,共3页GuangZhou Chemical Industry

基　　金：江苏省高等学校大学生实践创新训练计划(No:201618010XJ)

摘　　要：丙二腈分子中具有多个反应活性中心,是设计合成结构复杂多样的有机分子的理想原料。丙二腈参与的反应在具有重要生理和药理活性的杂环和碳环骨架的构筑中发挥着重要作用,在化学、医药和材料科学领域得到了广泛的应用,成为有机合成领域的研究热点之一。因此,对丙二腈参与的反应在有机合成中的应用展开综述,具有一定的理论研究意义。Malononitrile is an extraordinarily useful synthon for the construction of complex molecular skeletons and synthetic building blocks. The development of efficient approaches to chemically and biologically important products from malononitrile,while combining economic and environmental aspects has been an active topic in modern organic chemistry.More and more malononitrile-based reactions involving cascade processes have been reported,which provide powerful strategies for the synthesis of natural products and synthetic building blocks. The recent representative examples for preparing of important organic molecular were introduced.

关 键 词：丙二腈 有机合成 杂环 

分 类 号：O62[理学—有机化学]