肝动脉化疗栓塞联合超声引导下射频消融及经皮肝穿刺瘤内无水酒精注射治疗乏血供大肝癌的疗效分析  

Analysis on the Curative Effect of Hepatic Arterial Chemoembolization Combined with Ultrasound-Guided Radio Frequency Ablation and Percutaneous Transhepatic Intratumoral Anhydrous Ethanol Injection in the Treatment of Hypovascular Liver Cancer

作　　者：彭卫军[1] 蒋寒[1] 杨雯 张海青[1] 

机构地区：[1]湖北省潜江市中心医院放射科,湖北潜江433100

出　　处：《临床医学工程》2018年第1期11-12,共2页Clinical Medicine & Engineering

摘　　要：目的探讨肝动脉化疗栓塞(TACE)联合超声引导下射频消融(RFA)及经皮肝穿刺瘤内无水酒精注射(PEI)治疗乏血供大肝癌的临床疗效。方法选取2012年3月至2014年9月在我院行介入治疗的48例乏血供大肝癌患者,其中26例行TACE联合RFA、PEI(联合组),22例行TACE(对照组)。分析比较两组的临床疗效和生存率。结果术后联合组的治疗有效率和血清AFP下降率分别为84.62%和80.77%,均明显高于对照组的59.09%和50.00%(P<0.05)。联合组术后6、12、18、24个月的生存率分别为100.0%、92.3%、80.8%、65.4%,均明显高于对照组的77.3%、63.6%、45.5%、36.4%(P<0.05)。结论与单独行TACE比较,TACE联合RFA、PEI治疗乏血供大肝癌的疗效显著,可有效提高患者的生存率。Objective To explore the clinical curative effect of hepatic arterial chemoembolization （TACE） combined with ultrasound-guided radio frequency ablation （RFA） and percutaneous transhepatic intratumoral anhydrous ethanol injection （PEI） in the treatment ofhypovascular liver cancer. Methods 48 cases of patients with hypovascular liver cancer receiving interventional treatment in our hospital from March 2012 to September 2014 were selected. 26 cases of patients （combined group） received TACE combined with RFA and PEI, and another 22 cases of patients （control group） received TACE. The clinical curative effect and survival rate were analyzed and compared between two groups. Results The effective rate of treatment and AFP reduction rate of the combined group were respectively 84.62% and 80.77%, significantly higher than 59.09% and 50.00% of the control group （P〈0.05）. After operation, the survival rates after 6, 12, 18 and 24 months of the combined group were respectively 100.0%, 92.3%, 80.8% and 65.4%, significantly higher than 77.3%, 63.6%, 45.5% and 36.4% of the control group （P 〈0.05）. Conclusions Compared with only TACE, TACE combined with RFA and PEI in the treatment of hypovascular liver cancer has significant curative effect, which can effectively improve the survival rate of patients.

关 键 词：乏血供大肝癌 肝动脉化疗栓塞 射频消融 无水酒精 

分 类 号：R735.7[医药卫生—肿瘤]