立体定向放射治疗在妇科肿瘤中的应用进展  

Research progresses of stereotactic body radiotherapy in gynaecological cancers

作　　者：吕晓娟[1] 唐秋[1] 

机构地区：[1]浙江省肿瘤医院妇瘤科,杭州310022

出　　处：《中华放射医学与防护杂志》2018年第1期73-77,共5页Chinese Journal of Radiological Medicine and Protection

摘　　要：立体定向放射治疗（SBRT）是近年来兴起的放疗新技术，该技术的优点在于它能够在控制正常组织剂量的前提下提高肿瘤组织的剂量。SBRT在妇科肿瘤中的应用主要集中在盆腔复发灶、腹主动脉旁转移淋巴结、远处转移灶的局部治疗，可获得良好的局部控制，甚至一些患者有长期无病生存的可能。尽管SBRT有严格的剂量限制，但放疗后野内复发灶治疗后出现严重不良反应的概率较高。SBRT可以作为局部晚期宫颈癌体外放疗结束后，因某些因素而无法实施后装治疗的替代治疗。Stereotactic body radiation therapy（SBRT） is a new technology developed in recent years. The advantage of the technique resides in its ability to provide a high dose to tumor but spare normal tissues to an extent. The use of SBRT in gynecological cancers mainly concentrated in local treatment of pelvic recurrence, para-aortic lymph node metastasis and oligometastatic disease. SBRT boosts to macroscopic recurrences and oligometastatic disease can provide local control and a possibility of long-term disease-free survival in carefully selected patients. However, patients who received SBRT following prior irradiation, despite its tight conformality, were still confronted with significant morbidity. SBRT can be used as an alternative treatment for locally advanced cervical cancer after external-beam radiation therapy in patients who are unsuitable for brachytherapy.

关 键 词：立体定向放射治疗 妇科肿瘤 剂量分割 疗效 

分 类 号：R730.55[医药卫生—肿瘤]