ESWAN诊断子宫肌瘤的初步研究  

The preliminary study of ESWAN in diagnosis of uterine fibroids

作　　者：孙成凤[1] 吴准[1] 王习[1] 韩雨[1] 胡绮莉 门永超 王锡臻[1] 王滨[2] 

机构地区：[1]潍坊医学院附属医院影像中心,山东潍坊261042 [2]滨州医学院,山东烟台264003

出　　处：《实用放射学杂志》2018年第1期47-50,共4页Journal of Practical Radiology

基　　金：国家自然科学基金（81641074,81171303,30470518）;山东省自然科学基金（ZR2009CL046.ZR2010HQ029）;山东省优秀中青年科学家科研奖励基金（BS2012YY038）;山东省卫生厅科技发展项目（2011WSB29009,2011HW067）;滨州医学院山东省特色重点学科、山东省科技攻关项目（2007GG30002032,2008GG30002004）;潍坊医学院大学生科技创新基金（KX2015011,KX2016038,KX2017041）;潍坊市科技发展计划项目（2017YX054）.

摘　　要：目的 分析子宫肌瘤多回波采集重度T2＊ WI血管成像（ESWAN）的信号特征,评估 ESWAN对子宫肌瘤的诊断价值.方法 对37例子宫肌瘤患者行常规MRI和ESWAN,测量子宫肌瘤和子宫肌层的ESWAN各参数值,采用配对样本 t检验进行分析,使用受试者工作特征曲线（ROC曲线）评估ESWAN对子宫肌瘤的诊断价值.结果 子宫肌瘤的幅度值、相位值、R2＊值和T2＊值分别为1661.69 ± 45.24、（0.0067 ± 0.0077）Hz、（26.69 ± 1.04）Hz和（34.68 ± 1.73）ms.子宫肌层的幅度值、相位值、R2＊值和T2＊值分别为1790.95 ± 49.04、（0.0131 ± 0.0118）Hz、（22.35 ± 0.84）Hz和（42.53 ± 2.16）ms.子宫肌瘤的幅度值、相位值和T2＊值均低于子宫肌层（P=0.008、P=0.659和 P=0.002）,R2＊值高于子宫肌层（P=0.001）.幅度值、相位值、R2＊值和 T2＊值诊断子宫肌瘤的曲线下面积（AUC）分别为0.604、0.553、0.666和0.662.结论 ESWAN能反映子宫肌瘤和子宫肌层间的信号差异,但独立诊断子宫肌瘤的价值不高.Objective To explore the diagnostic value of ESWAN in uterine fibroids by analyzing the ESWAN signal of uterine fibroid. Methods Conventional MRI and ESWAN were carried out in thirty-seven patients with uterine fibroids.The differences of ESWAN indexes between uterine fibroids and myometrium were analyzed by paired t-test.The value of ESWAN on diagnosing uterine fibroids was analyzed by receiver operating characteristic curve（ROC curve）.Results The magnitude value,phase value,R2＊ value and T2＊value of uterine fibroids were 1 661.69 ± 45.24,（0.006 7 ± 0.007 7）Hz,（26.69 ± 1.04）Hz and（34.68 ± 1.73）ms,respectively.The magnitude value,phase value,R2＊ value and T2＊ value of myometrium were 1 790.95 ± 49.04,（0.013 1 ± 0.011 8）Hz,（22.35 ± 0.84）Hz and（42.53 ± 2.16）ms.The magnitude value,phase value and T2＊ value of uterine fibroids were lower than those of myometrium （P=0.008,P=0.659 and P=0.002）.While the R2＊ value of of uterine fibroids was higher than that of myometrium（P=0.001）. The area under curve（AUC）of magnitude value,phase value,R2＊ value and T2＊ value were 0.604,0.553,0.666 and 0.662.Conclusion ESWAN can show the differences between uterine fibroids and myometrium ,while the ability to independently diagnose uterine fibroids was modest.

关 键 词：子宫肌瘤 磁敏感加权成像 多回波采集 

分 类 号：R737.33[医药卫生—肿瘤] R445.2[医药卫生—临床医学]