超声条件下以抗坏血酸催化合成乙酰水杨酸  

Synthesis of Acetylsalicylic Acid Catalyzed by Ascorbic Acid under Ultrasonic

作　　者：陈倩[1] 刘晶[2] 李倩[1] 高明明[1] 

机构地区：[1]西北大学现代学院,陕西西安710130 [2]西安外事学院,陕西西安710077

出　　处：《化工设计通讯》2018年第1期125-125,150,共2页Chemical Engineering Design Communications

摘　　要：以水杨酸、乙酸酐作为原料,采用抗坏血酸作催化剂,超声辐射条件下合成乙酰水杨酸。重点考查了催化剂种类、抗坏血酸用量、超声时间等对反应收率的影响,优化后乙酰水杨酸产率可达80%。Salicylic acid and acetic anhydride were used as raw materials, and ascorbic acid was used as catalyst to synthesize acetylsalicylic acid under ultrasonic condition.The effects of catalyst＇ s type, ascorbic acid dosage and ultrasonic time were investigated. The optimum yield of acetyl salicylic acid was 80%.

关 键 词：乙酰水杨酸 合成 抗坏血酸 超声 

分 类 号：TQ466.3[化学工程—制药化工]