三维超声测量胎儿胼胝体-小脑幕夹角的方法及临床价值  

Fetal Corpus Callosum-tentorium Angle Measured with Three-dimensional Ultrasonography and Its Clinical Value

作　　者：苏淇琛[1] 杨海南 吕国荣[1,2] 

机构地区：[1]福建医科大学附属第二医院超声科,福建省泉州市362000 [2]福建省泉州医学高等专科学校母婴健康服务应用技术协同创新中心

出　　处：《中国超声医学杂志》2018年第1期50-53,共4页Chinese Journal of Ultrasound in Medicine

摘　　要：目的建立中晚孕期正常胎儿胼胝体-小脑幕夹角(CTA)正常参考值范围,并评估其在单纯性枕大池增宽(MCM)及DWM中的应用价值。方法采用三维超声容积对比成像(3DUS-VCI)技术测量350例21~32孕周正常单胎胎儿CTA,分析其与孕周的关系,并按照上述方法对14例MCM和12例DWM胎儿进行评估。结果 (1)正常胎儿CTA与孕周不存在明显相关(r=0.014,P>0.05);(2)3DUS-VCI测量CTA有良好的重复性及一致性;(3)MCM胎儿CTA与正常胎儿组无明显差异,DWM胎儿CTA较正常组及MCM组明显减小(32.76±6.23)°vs(55.82±5.32)°,t=25.12,P<0.05;(32.76±6.23)°vs(56.66±4.18)°,t=26.04,P<0.05。结论运用3DUS-VCI技术测量胎儿CTA的方法是可行的,有助于单纯性枕大池增宽和Dandy-Walker畸形的鉴别诊断。Objective To establish the ranges of normal reference values of fetal corpus callosum- tentorium an- gle（CTA） in normal fetuses, and to evaluate their clinical values in the diagnosis of mega cisterna magna（MCM） and Dandy-Walker malformation（DWM）. Methods Totally 350 normal singleton fetuses between 21 and 32 weeks of ges- tation were enrolled. Three dimensional ultrasonography volume contrast imaging （3DUS-VCI） was used to measure their CTA, the correlations of CTA with gestational age were investigated. The CTA of 14 fetuses with MCM and 12 fetuses with DWM were also measured and were compared with those of the normal fetuses. Results In these normal fetuses, the CTA showed no correlations with gestational age （r= 0. 014, P〉0.05）. The CTA of 14 fetuses with MCM were not significantly different from those of normal fetuses, while the CTA of 12 fetuses with DWM were sig- nificantly smaller than those of normal fetuses and the fetuses with MCM（32.76 ± 6.23）°vs （55.82 ± 5.32）°, t = 25.12,P〈0.05;（32.76±6.23）°vs （56.66±4.18）°,t=26.04,P〈0.05. The repeatability of the same physician and the consistency between two different physicians were good. Conclusions VCI is feasible for measuring the CTA of fetuses. The measuring of the CTA can help differentiate MCM from DWM.

关 键 词：三维超声 胎儿 胼胝体-小脑幕夹角 单纯性枕大池增宽 DANDY-WALKER畸形 

分 类 号：R445.1[医药卫生—影像医学与核医学] R714.5[医药卫生—诊断学]