PET/MRI在胰腺肿瘤中的应用  

The application of PET/MRI in pancreatic neoplasms

作　　者：李旭东 林晓珠[1] 

机构地区：[1]上海交通大学医学院附属瑞金医院放射科,上海200025

出　　处：《国际医学放射学杂志》2018年第1期59-61,84,共4页International Journal of Medical Radiology

摘　　要：PET/MRI是一种将PET和MRI融合的新型影像诊断技术,其整合了PET提供的人体生理代谢、分子信息和MRI提供的功能及解剖形态信息。相较于CT,MRI具有更高的软组织对比度,可多参数成像,且无辐射。PET/MRI在胰腺癌病灶检测、术前分期和预后评估方面优于PET/CT。^(68)Ga标记的生长抑素受体显像剂PET/MRI能够提高胰腺神经内分泌肿瘤的检测和诊断能力。新型显像剂的研发和应用能够提高胰腺肿瘤PET/MRI的特异性和精准性。就PET/MRI在胰腺癌的诊断、分期及疗效监测的应用价值及其对胰腺神经内分泌肿瘤的研究进展予以综述。PET/MRI is a new medical imaging technology that can obtain hybrid images of PET and MRI simultane-ously,which integrates human physiological metabolism and molecular information from PET with functional and anatomical information from MRI.MRI has many advantages compared with computed tomography （CT）,such as better soft tissue contrast, multiple parameters and no radiation.Researches showed that PET/MRI is superior to PET/CT in the detection, preoperative staging and prognosis of pancreatic cancers. PET/MRI using Somatostatin（SST） receptor with 68-Gallium （68Ga）-labeled can enhance the detection and diagnosis of pancreatic neuroendocrine tumors. The application of newly developed contrast media can improve specificity and accuracy of PET/MRI in diagnosing pancreatic tumors.In this paper, the values of PET/MRI in di-agnosis, staging and evaluating therapeutic effect in pancreatic cancer and progress of PET/MRI researches in pancreatic neu-roendocrine tumors were reviewed.

关 键 词：胰腺肿瘤 正电子发射体层成像 磁共振成像 体层摄影术 X线计算机 分子成像 18F-氟脱氧葡萄糖 

分 类 号：R735.9[医药卫生—肿瘤] R445.6[医药卫生—临床医学]