麦冬化学成分及药理作用研究进展  

Research progress on chemical constituents and pharmacological effects of Ophiopogon japonicas

作　　者：彭婉 马骁[1] 王建[1] 曾南[1] 董泰玮 李雷 李敏[1] 

机构地区：[1]成都中医药大学药学院,中药材标准化教育部重点实验室,四川成都611137

出　　处：《中草药》2018年第2期477-488,共12页Chinese Traditional and Herbal Drugs

基　　金：国家中药标准化行动项目“川贝母、半夏等7种中药饮片标准化建设”(ZYBZH-Y-SC-40);四川省科技厅科技支撑项目“麦冬整合式产业链综合开发研究”(2015SZ0033);国家基础科学人才培养基金(J1310034)

摘　　要：麦冬在中国分布广泛,资源丰富,是一种利用价值很高的药用植物,具有养阴生津、润肺清心的功效。现代研究发现麦冬的化学成分主要包括甾体皂苷类、高异黄酮类、多糖类等;具有降血糖、保护心血管系统、增强免疫力、抗皮肤衰老、抗炎、抗肿瘤等药理作用。对麦冬的化学成分、药理作用进行综述,为麦冬的开发利用提供参考。Ophiopogon japonicus is widely distributed in China and rich in resources, and is a kind of medicinal plants with great utilization value. It could nourish yin, promote body fluid production, moisten the lung, ease the mind, and clear away heart fire. Modem research showed that there are several secondary metabolites, such as steroidal saponins, homoisoflavonoids and polysaccharides. Its pharmacological research mainly focused on the hypoglycemic effect, cardiovascular protection, enhanced immunity, anti-aging, anti-inflammatory, and antitumor effect. In this paper, the chemical compositions and pharmacological activities of O. japonicas were summarized, in order to provide reference for further study and application of O. japonicas.

关 键 词：麦冬 甾体皂苷类 高异黄酮类 多糖类 降血糖 保护心血管系统 增强免疫力 

分 类 号：R282.71[医药卫生—中药学]