定量检测血清降钙素原在诊断肝衰竭患者腹腔感染细菌类型中的价值  

Value of Quantitative Detection of Serum Procalcitonin in the Diagnosis of Peritoneal Infection Bacteria in Patients with Liver Failure

作　　者：詹金美[1] 林欢 孙家敏[1] 

机构地区：[1]龙岩市第二医院感染科一区,福建龙岩364000

出　　处：《中外医疗》2017年第28期34-36,共3页China & Foreign Medical Treatment

摘　　要：目的对定量检测血清降钙素原在诊断肝衰竭患者腹腔感染细菌类型中的价值进行评价分析,为今后的临床诊断工作,提供有价值的参考依据。方法方便选择2015年1月—2016年12月间该院收治的获得明确诊断的肝衰竭患者128例作为研究对象,将其按照是否发生腹腔感染分成感染组与非感染组,感染组患者按照感染细菌类型分成革兰阳性菌组、革兰阴性菌组两个亚组,对所有患者均进行血清降钙素原水平检测,并对检测结果进行了统计分析。结果感染组血清降钙素原水平为(0.78±0.14)ng/m L,非感染组血清降钙素原水平为(0.23±0.15)ng/m L,感染组检测结果较对照组发生明显升高(P<0.05);革兰阳性菌感染组患者血清降钙素原水平集中在0.5~2.0 ng/m L之间,革兰阴性菌感染组患者血清降钙素原水平集中在≥2.0 ng/m L,革兰阴性菌感染组患者血清降钙素原水平明显高于革兰阳性菌感染组(P<0.05)。结论肝衰竭患者在出现腹腔感染后,血清降钙素原水平发生显著升高,定量检测血清降钙素原水平,对于腹腔感染诊断以及感染细菌类型判断等均具有十分重要的意义,临床价值显著,值得关注并推广。Objective This paper tries to evaluate the value of quantitative detection of serum procalcitonin in the diagnosis of bacterial infection in patients with hepatic failure and to provide a valuable reference for future clinical diagnosis.Methods From January 2015 to December 2016 in this hospital,128 cases diagnosed with liver failure were convenient selected as the research objects,according to the occurrence of abdominal infection,these objects were divided into the infection group and non infection group,and the infection group was divided into two sub-groups of gram positive bacteria and gram negative bacteria group.All patients were tested for serum procalcitonin level,and the detection results were statistically analyzed.Results The serum procalcitonin level in the infection group was（0.78±0.14）ng/mL,and that of the non infection group was（0.23±0.15）ng/mL,the infection group test results increased significantly greater than the control group（P〈0.05）;the serum procalcitonin level of the gram positive bacteria infection group was between 0.5 and 2.0 ng/mL,the serum procalcitonin level in the gram negative bacteria infection group was more than or equal to 2.0 ng/mL,serum procalcitonin levels in the gram negative bacteria infection group were significantly higher than that of gram positive bacteria infection group（P〈0.05）.Conclusion Patients with liver failure in abdominal infection,the serum procalcitonin levels are significantly increased,the quantitative detection of serum procalcitonin level for abdominal infection diagnosis and bacterial infection type judgment is very significant,with significant clinical value,so it is worthy of attention and promotion.

关 键 词：血清降钙素原 肝衰竭 腹腔感染 细菌类型 临床诊断 

分 类 号：R575[医药卫生—消化系统]