应用Conners父母问卷对癫痫儿童行为问题的研究及相关分析  

Study and Correlative Analysis on the Behavioral Problems of Children with Epilepsy by Conners Parents’ Questionnaire

作　　者：刘芳[1] 姚宝珍[1] 牛萍[1] 王世红[1] 凌伟[1] 王军陵[1] 

机构地区：[1]武汉大学人民医院儿科

出　　处：《武汉大学学报（医学版）》2018年第2期178-183,共6页Medical Journal of Wuhan University

摘　　要：目的：探讨癫痫儿童行为问题状况及不同临床特征对行为问题的影响及相关分析。方法：应用Conners父母问卷对50例癫痫儿童和52例健康对照儿童进行行为问题分析,并根据不同临床特征对癫痫儿童共患行为问题作单因素和多因素分析。结果：癫痫组行为问题检出率34%,癫痫组Conners父母问卷的6个因子得分均高于对照组和中国常模（P〈0.05）。癫痫儿童中,9-11岁组的学习问题得分最高,早产儿的焦虑因子得分高于非早产儿,剖宫产儿的冲动-多动因子得分高于顺产儿,全面性发作组的品行问题因子得分高于局灶性发作组,病程〉2年组的学习问题因子高于病程≤2年组（P均〈0.05）。首次发作年龄与品行问题因子得分呈负相关,发作频率与焦虑、病程与学习问题、用药数量与品行问题的因子得分均呈正相关。多因素Logistic回归分析显示剖宫产、发作频率高、联合用药是影响癫痫患儿行为问题的危险因素,OR（95%CI）分别为7.278（1.159-45.697）、2.427（1.312-4.489）、20.170（1.076-378.003）。结论：癫痫儿童共患行为问题的发生率较高,且不同临床特征的癫痫患儿的行为问题各因子得分差异显著,剖宫产、发作频率越高、联合用药是癫痫患儿共患行为问题的高危因素。Objective： To investigate the behavioral problems of children with epilepsy and the impact of different clinical characteristics on behavioral problems. Methods： The behavioral problems of 50 children with epilepsy and 52 healthy controls were evaluated by Conners parents＇ questionnaire. Univariate and multivariate analysis were implyed in epilepsy children with behavioral problems according to different clinical characteristics. Results： The detection rate of behavior problems in epilepsy children was 34~/00, and the scores of six factors in the epilepsy group were significantly higher than that in control group and the Chinese scale norm （P（0.05）. In the epilepsy group, the score of learning problems was highest in the 9-11 years old group, the score of anxiety in premature children was higher than that in the non-premature children, the score of impulsive-hy- peractivity in the cesarean children was higher than that in the natural birth children, the score of moral behavior problems in generalized seizure group was higher than the focal seizure group, and the score of learning problems in duration time^2 years group was higher than^2 years group （P all^0.05）. There was a negative correlation between age of first outbreak and score of moral behavior problems, and there were positive correlation between onset frequency and anxiety, du- ration of illness and learning problem, medication numbers and moral behavior problems. Multi- variate logistic regression analysis showed that cesarean section, onset frequency and combination medication were the risk factors for behavioral problems in children with epilepsy. The OR（95~ CI） was 7. 278（1. 159-45. 697）, 2. 427 （1. 312-4. 4489）, 20. 170 （1. 076 to 378. 003） respectively. Conclusion： The incidence of comorbid behavior problems in children with epilepsy is high, and the difference on scores of behavioral problems of children with epilepsy were significant among different clinical characteristics. Cesarean section, onset frequency an

关 键 词：癫痫 行为问题 CONNERS量表 共患病 

分 类 号：R742.1[医药卫生—神经病学与精神病学]