L-精氨酸改性淀粉的制备及其抗菌薄膜的性能  

Preparation of L-arginine Modified Starch and Properties of Its Antibacterial Films

作　　者：张昊[1] 刘叶[1] 张毅[1] 程博闻 牛芊芊 周省 

机构地区：[1]天津工业大学纺织学院,天津300387 [2]天津工业大学天津市改性与功能纤维重点实验室,天津300387

出　　处：《精细化工》2018年第2期303-311,共9页Fine Chemicals

基　　金：国家自然科学基金(51503147);国家级现代农业产业技术体系专项项目(CARS-43-E-2)~~

摘　　要：以玉米淀粉（St）、丙烯酸甲酯（MA）与L-精氨酸（L-Arg）为原料,采用酯化-氨解两步法,制备了具有抑菌性能的精氨酸改性淀粉（St MA-Arg）。阐述了反应机理,用拉曼光谱、^13CNMR、XRD与GPC表征了产物的结构,通过单因素实验优化了反应条件。以St MA-Arg为原料制备了抗菌膜,考察了L-Arg固载率（IR）对薄膜的亲疏水性能、力学性能及抑菌性能的影响。结果表明,St MA-Arg薄膜的力学性能较天然淀粉膜显著改善,同时疏水性增强。固载率（IR）为7.48%的St MA-Arg及其薄膜对大肠杆菌（E.coli）显示出明显的抑菌活性,且膜的抑菌较小,属接触式抑菌。土壤失重实验结果显示,St MA-Arg（IR=7.48%）薄膜40d后的失重率为27.90%,远小于天然淀粉膜（40 d失重率为72.15%）。有望成为一种潜在的环境修复材料的基体。A series of L-arginine （L-Arg） modified starch （StMA-Arg） with antibacterial activity were prepared by esterification and ammonolysis with corn starch （St）, methyl acrylate （MA） and L-Arg as raw materials. The reaction mechanism was discussed. The products were characterized by Raman spectroscopy （ RAM）, 13 C nuclear magnetic resonance （ 13 CNMR） spectroscopy, X-ray diffraction （XRD） and gel permeation chromatography （ GPC ） , and the reaction conditions were optimized by single factor experiments. Subsequently, antibacterial films were prepared using StMA-Arg as raw material. The effects of L-Arg immobilization ratio （IR） on the hydrophobic properties, mechanical properties and antibacterial activity of films were investigated. The results showed that the mechanical properties of StMA-Arg film were significantly improved compared with native starch film. Meanwhile, the hydrophobicity of film was enhanced. When IR was 7.48%, StMA-Arg and its film showed obvious antibacterial activity against Escherichia coli, and the bacteriostatic circle of film was small, which belonged to contact bacteriostasis. The results of weight loss experiments indicated that the weight loss rate of StMA-Arg （IR =7.48% ） film was 27.90% after 40 days, which was much lower than that of native starch film （72. 15% ）. The prepared StMA-Arg will be a potential substrate for environmental restoration material.

关 键 词：淀粉 精氨酸 固载 抑菌膜 环境修复 淀粉化学品 

分 类 号：O631.3[理学—高分子化学]