内镜黏膜下剥离术治疗早期胃癌中脉管癌栓相关因素分析  

Relative factors analysis on lymphovascular invasion of early gastric cancer treated by endoscopic submucosal dissection

作　　者：张波[1,2] 令狐恩强[2] 柴宁莉 卢忠生 杨竞 冯秀雪 陈亚东 杜红 孟江云 王红斌 王向东 朱静 

机构地区：[1]解放军总医院消化科,北京100853 [2]中共中央办公厅警卫局保健处,北京100036

出　　处：《临床军医杂志》2018年第1期34-36,40,共4页Clinical Journal of Medical Officers

基　　金：北京市科委项目(D141100000414003)

摘　　要：目的分析内镜黏膜下剥离术(ESD)治疗早期胃癌(EGC)患者中脉管癌栓的相关因素。方法回顾性分析自2006年11月至2016年1月经ESD治疗的261例EGC患者的临床病理资料,对脉管癌栓阳性患者的存活情况进行随访,并分析影响脉管癌栓的相关因素。结果本研究261例EGC患者中,9例患者脉管癌栓阳性,阳性率为3.4%(9/261)。其中,7例追加外科手术治疗,2例未接受手术治疗。随访时间31~108个月,患者均获得长期存活,存活率为100.0%。脉管癌栓与肿瘤分化程度、浸润深度具有相关性。结论分化程度差、黏膜下侵犯的EGC患者接受ESD治疗时应警惕脉管癌栓的发生。Objective To analyze the relative factors of lymphovascular invasion of early gastric cancer（ EGC） treated by endoscopic submucosal dissection（ ESD）. Methods A retrospective study was performed on 261 cases of EGC patients who were admitted and underwent ESD from November 2006 to January 2016. The conduct follow-up was performed on survival status of patients with positive lymphovascular invasion and the relative factors were analyzed. Results Among the total 261 cases of EGC patients,9 cases showed positive lymphovascular invasion,with a positive incidence of 3. 4%（ 9/261）,including 7 cases were given additional surgery,2 cases were not given additional surgery. The follow-up visit lasted for a period of 31 to 108 months,the survival rate was 100. 0%. The lymphovascular invasion was relevant to tumor differentiation degree and invasion depth. Conclusion Close attention should be given to the possibility of lymphovascular invasion when giving ESD treatment to EGC patients with poor differentiation degree and submucosal invasion.

关 键 词：早期胃癌 内镜黏膜下剥离术 脉管癌栓 

分 类 号：R735.2[医药卫生—肿瘤]