跨壶腹部支架植入术治疗低位恶性胆道梗阻的通畅性分析  

Percutaneous transampulla stent implantation for the treatment of lower malignant obstructive jaundice: an analysis of related factors influencing the stent patency

作　　者：张金星[1] 祖庆泉[1] 卢光东[1] 刘圣[1] 施海彬[1] 

机构地区：[1]南京医科大学第一附属医院介入放射科,210029

出　　处：《介入放射学杂志》2018年第2期137-140,共4页Journal of Interventional Radiology

摘　　要：目的探讨跨壶腹部支架植入术治疗低位恶性胆道梗阻与支架通畅时间相关的危险因素。方法回顾性分析2010年1月至2016年3月接受跨壶腹部胆道支架植入术治疗的低位恶性胆道梗阻患者104例,选择性别、年龄、原发肿瘤类型、术前引流、血清总胆红素、白蛋白、丙氨酸转氨酶、天冬氨酸转氨酶、白细胞计数、血小板计数、血红蛋白以及胆管狭窄长度作为研究参数,评估影响该类患者术后支架通畅时间的相关危险因素。结果单因素Cox回归分析显示原发肿瘤类型,血清白蛋白,白细胞计数,胆管狭窄长度4个因素是影响该类患者术后支架通畅时间的相关因素;多因素Cox回归分析显示原发肿瘤类型和胆管狭窄长度是影响该类患者术后支架通畅时间的重要因素。结论在对跨壶腹部支架植入术治疗低位胆道梗阻时,原发肿瘤类型和胆管狭窄长度可能是影响患者支架通畅时间的相关因素,对评估该类患者术后支架通畅时间有重要的参考意义。Objective To evaluate percutaneous transampulla stent implantation in treating lower malignant obstructive jaundice, and to discuss the related factors that may influence the stent patency time.Methods The clinical data of a total of 104 patients with lower malignant obstructive jaundice, who received percutaneous transampulla stent implantation during the period from January 2010 to March 2016,were retrospectively analyzed. The parameters, including gender, age, primary tumor type, preoperative external drainage, total bilirubin（TBIL）, albumin（ALB）, glutamic-pyruvic transaminase（ALT）, glutamic-oxaloacetic transaminase（AST）, white blood cell（WBC） count, platelet（PLT） count, hemoglobin（HGB）and length of biliary stricture, were used to evaluate the risk factors related to postoperative patency time.Results Single Cox regression analysis showed that primary tumor type, ALB, WBC count, length of biliary stricture were the related factors that significantly affected the stent patency time. The Cox regression analysis further indicated that primary tumor type and length of biliary stricture were the important related factors that significantly affected the stent patency time. Conclusion In treating lower malignant obstructive jaundice with percutaneous transampulla stent implantation, primary tumor type and length of biliary stricture may be the important related factors that affect the stent patency time. These parameters are of great value in estimating the stent patency time.

关 键 词：低位胆道梗阻 壶腹部 支架 通畅时间 

分 类 号：R735.8[医药卫生—肿瘤]