醋酸锰催化合成萘并噻唑衍生物研究型综合实验  

A Research-Oriented Comprehensive Chemistry Experiment of Preparation of Naphthothiazole Derivatives by Manganese Acetate

作　　者：刘天宝[1] 彭艳芬[1] 

机构地区：[1]池州学院化学与材料工程学院

出　　处：《化学教育（中英文）》2018年第4期31-34,共4页Chinese Journal of Chemical Education

基　　金：地方高校本科专业综合改革试点项目(ZG0243);安徽省教育厅自然科学基金重点项目(KJ2016A512);安徽省高校优秀青年人才支持计划重点项目(gxyqZD2016372);池州学院教研项目(2016XJYXM71)

摘　　要：设计了“醋酸锰（Ⅲ）催化合成2～邻氯苯甲酰氨基萘并[1，2-d]噻唑”研究型综合化学实验，以自制的醋酸锰（Ⅲ）为催化剂，催化氧化1-萘基～3-邻氯苯甲酰基硫脲合成2-邻氯苯甲酰氨基萘并[1，2～d]噻唑。通过该实验项目的教学，可使学生掌握醋酸锰（Ⅲ）、1-萘基-3-邻氯苯甲酰基硫脲和2-邻氯苯甲酰氨基萘并[1，2-d]噻唑的合成方法，掌握有机化合物结构表征的方法，可以培养学生的实践动手能力、科研创新能力以及综合运用知识的能力。该实验项目集无机合成实验、有机合成实验和仪器分析实验于一体，具有较强的可操作性和实用性，可作为基础化学研究型综合化学实验或开放性实验开设。A research-oriented comprehensive chemistry experiment of preparation of 2-0 chlorobenzamido naphtho [1, 2-d] thiazole by manganese acetate （Ⅲ ） is introduced. The self- prepared manganese acetate （Ⅲ） as catalyst is applied for catalyzing 1-naphthyl-3-o chloro- benoylthiourea to synthesize 2-o-chlorobenzamido naphtho [1,2-d] thiazole. Through this ex- periment teaching, students can master the synthesis methods of the manganese acetate （ Ⅲ ）, 1- naphthyl-3-o-chlorobenoylthiourea and 2-o-chlorobenzamido naphtho [1,2-d] thiazole, and can grasp general methods of organic compounds＇ structure characterization. It is more important that the experiment teaching can cultivate students＇ practical ability, research and creative abili- ty, and students＇ comprehensive ability to use knowledge. This experiment gathers inorganic synthesis experiment, organic synthesis experiment and instrumental analysis experiment, and has good operability and practicability. It can be established as a research-oriented comprehensive chemical experiment or open experiment.

关 键 词：醋酸锰 综合化学实验 硫脲 萘并噻唑 

分 类 号：G642[文化科学—高等教育学] O626-4[文化科学—教育学]