L-薄荷醇亚砜类配体的合成  

Synthesis of L-menthol Sulfoxide Ligands

作　　者：付宇鑫 

机构地区：[1]合肥工业大学化学与化工学院,安徽合肥230009

出　　处：《安徽化工》2018年第1期53-55,共3页Anhui Chemical Industry

摘　　要：亚砜类化合物作为手性配体催化不对称反应是目前研究最为活跃的领域之一。L-薄荷醇作为一种具有药理作用的天然化合物,具有薄荷香气并有清凉的作用。薄荷醇分子中有三个不对称碳原子,对于合成手性配体有着至关重要的作用。利用自行设计合成的L-薄荷醇的亚砜类配体,与铜、钯等金属络合物原位组合形成催化体系,用此体系可以催化一系列反应。Chiral ligands based on sulfoxid in asymmetric reaction have recently become an increasingly active research area, L-menthol as a pharmacological effect of natural compounds, with mint aroma and a cool effect. There are three asymmetric carbon atoms in the menthol molecule that play a crucial role in the synthesis of chiral ligands. In this paper, a series of reactions were catalyzed by in-situ combination of metal complexes such as copper and palladium using a sulfoxide-based ligand of L-menthol, which was synthesized and synthesized.

关 键 词：L-薄荷醇 手性配体 亚砜类化合物 

分 类 号：TQ655[化学工程—精细化工]