一种新的无催化剂条件下的2,3-喹啉二羧酸酯的合成  

A New Catalyst-Free Synthesis of 2,3-Dicarboxylic Ester Quinoline Derivatives

作　　者：王彬 叶文波 晏子聪 万常峰[1] 侯豪情[1] 汪志勇[2] 

机构地区：[1]江西师范大学化学化工学院,南昌330022 [2]中国科学技术大学化学系,合肥230026

出　　处：《有机化学》2018年第2期504-508,共5页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(Nos.21402068;21574060;21472177)资助项目~~

摘　　要：无催化剂条件下,利用邻氨基二苯甲酮衍生物和丁炔二酸酯作为反应原料,二甲基亚砜(DMSO)作为溶剂,高效地构建2,3-喹啉二羧酸酯类化合物.并且根据反应的结果,对可能的反应机理进行了初步的探究.A high efficient method for the synthesis of 2,3-dicarboxylic ester quinoline derivatives which employed o-amino diphenyl methylone derivatives and acetylenedicarboxylic esters as the reaction substrates was developed. This method possessed the character of catalyst-free and mild reaction conditions. Proposed mechanism was also studied according to the reaction result.

关 键 词：喹啉衍生物 无催化剂 绿色合成 

分 类 号：O626.323[理学—有机化学]