肠内营养联合肠外营养治疗老年胃癌患者的临床研究  

Enteral nutrition combined with parenteral nutrition for gastric cancer in elderly patients

作　　者：黄东平[1] 葛骖 孙竹峰[1] 朱国英[1] 方青 周庚仁[1] 黄建伟[1] 陈曦[1] 潘莎漪 方敏彦 汤庆娅 

机构地区：[1]上海市普陀区人民医院普通外科,上海200060 [2]上海交通大学附属新华医院临床营养科,上海200092

出　　处：《中国肿瘤临床与康复》2018年第1期6-9,共4页Chinese Journal of Clinical Oncology and Rehabilitation

基　　金：上海市卫生计生委临床营养重点专科建设项目(ZK2015B19)

摘　　要：目的探讨肠内营养结合肠外营养治疗老年胃癌患者的临床效果。方法选取2014年6月至2016年5月间上海市普陀区人民医院收治的80例胃癌手术患者,采用抽签法分为治疗组与对照组,每组40例。对照组患者采用全肠外营养治疗,治疗组患者在肠内营养基础上结合肠外营养治疗。比较两组患者手术前后的营养指标、术后并发症发生率及术后恢复情况。结果治疗组患者术后并发症发生率为7.5%,低于对照组的25.0%,两组比较,差异有统计学意义(P<0.05)。治疗组患者血红蛋白(HGB)、总蛋白(TP)和白蛋白(ALB)数值均优于对照组,差异均有统计学意义(均P<0.05);两组患者白细胞(WBC)和前白蛋白(PA)比较,差异无统计学意义(P>0.05)。治疗组患者通气时间为(3.12±1.05)d,显著短于对照组的(4.45±1.26)d,差异有统计学意义(P<0.05);两组患者住院时间、进流质时间和住院费用比较,差异均无统计学意义(均P>0.05)。结论肠内营养结合肠外营养治疗老年胃癌手术患者,临床疗效显著,可有效改善营养代谢,安全性高,值得临床推广应用。Objective To investigate the clinical efficacy of enteral nutrition combined with parenteral nutrition in the treatment of gastric cancer in the elderly. Methods Eighty patients with gastric cancer were selected at Shanghai Putuo People＇s Hospital from June 2014 to May 2016. The lottery drawing method was used and the patients were divided into a treatment group and a control group with 40 patients in each group. The treatment group was treated with the combination therapy of parenteral nutrition with enteral nutrition and the control group was treated with parenteral nutrition. The nutrition index,postoperative complication and postoperative recovery were compared between the two groups. Results The incidence of postoperative complications in the treatment group was 7. 5%,which was lower than 25. 0% of the control group（ P〈0. 05）. The hemoglobin（ HGB）,total protein（ TP） and albumin（ ALB） values were better in the treatment group than in the control group（ P〈0. 05）. There was no statistically significant difference in white blood cells（ WBC） and prealbumin（ PA） between the two groups（ P〈0. 05）. Ventilation time in the treatment group was（ 3. 12 ± 1. 05） d which was significantly shorter than（ 4. 45 ± 1. 26） d of the control group（ P〈0. 05）. There was no statistically significant difference in hospitalization time,liquid time and hospitalization expenses between the two groups（ P〉0. 05）. Conclusion Enteral nutrition combined with parenteral nutrition shows significant clinical efficacy. It can effectively improve its nutritional metabolism with high safety in elderly patients with gastric cancer surgery. It is worth popularizing in clinical treatment.

关 键 词：胃肿瘤 老年 肠内营养 肠外营养 安全性 

分 类 号：R735.2[医药卫生—肿瘤]