纳米羟磷灰石在牙体修复和牙髓治疗领域的应用  

Application of nano-hydroxyapatite in the clinical treatment of oral diseases

作　　者：罗惟丹 李明云[1] 周学东[1] 程磊[1] 

机构地区：[1]口腔疾病研究国家重点实验室国家口腔疾病临床医学研究中心四川大学华西口腔医院牙体牙髓病科,成都610041

出　　处：《国际口腔医学杂志》2018年第2期192-198,共7页International Journal of Stomatology

基　　金：国家国际科技合作专项项目(2014DFE30180)~~

摘　　要：纳米羟磷灰石与天然骨及牙釉质中的羟磷灰石晶体相似,具有良好的物理和化学性质、生物相容性、骨结合性等,在口腔疾病治疗领域应用广泛。本文对纳米羟磷灰石在牙体修复及牙髓治疗方面的相关研究进展进行综述,涉及牙科材料改性、再矿化、牙齿脱敏、牙髓治疗、牙髓组织工程学等方面。现有的研究表明,纳米羟磷灰石在口腔疾病治疗领域具有较大的潜力。Nano-hydroxyapatite （nHA） shows a structure similar to that of hydroxyapatite crystal in human bone tissue and tooth enamel. Given its excellent physical and chemical properties, biocompatibility and osseointegration, nHA has been extensively applied in the clinical treatment of oral diseases. This article reviewed the most recent findings about nHA in stomatology, including the modification of restorative materials, tooth remineralization, tooth desensitization, pulp canal therapy and pulp tissue engineering. These studies are indicative of the future remarkable significance of nHA in stomatology.

关 键 词：纳米羟磷灰石 材料改性 再矿化 脱敏 牙髓治疗 牙髓组织工程 

分 类 号：R781.05[医药卫生—口腔医学]