功能性胃十二指肠病与胃食管反流病  

Functional gastrointestinal disorders and gastroesophageal reflux disease

作　　者：李连勇[1] 屈昌民[1] 吴玮[2] 

机构地区：[1]中国人民解放军第306医院消化内科,北京100101 [2]中国人民解放军第306医院耳鼻咽喉头颈外科,北京100101

出　　处：《中国医学文摘（耳鼻咽喉科学）》2018年第1期29-32,共4页Chinese Medical Digest(Otorhinolaryngology)

摘　　要：功能性胃十二指肠病是最常见的消化系统疾病之一。该部分患者有相关不适症状,但无器质性疾患,常伴有动力异常、内脏高敏感、黏膜及免疫功能改变及肠道菌群失调等变化。当胃十二指肠功能障碍时,并发或引起动力紊乱,导致异常液体或气体反流发生,从而引起胃食管或气道反流。依据功能性胃肠病罗马IV标准,功能性胃十二指肠病可以分为4个类型,即功能性消化不良、嗳气症、慢性恶心和呕吐症、成人反刍综合征。本文简要综述该4种类型功能性胃十二指肠疾病的定义、临床诊断、病理生理过程,用以探讨其与胃食管反流病或胃气道反流病的可能关系。Functional gastrointestinal disorders （FGIDs） are the most common diagnoses in gastroenterology. They often occur in combination including motility disturbance, visceral hypersensitivity, altered mucosal and immune function, altered gut microbiota, and altered central nervous system processing. Under these abnormal circumstances, a noxious blend of acid, bile, and digestive enzymes will reflux into the esophagus and even airway from the stomach and elicit symptoms. We aim to provide a concise overview of the four categories of functional gastroduodenal disorders to seek the theoretical relationship between functional gastrodu- odenal disorders and gastroesophageal reflux disease （GERD） or gastroesophago-airway reflux disease （GARD） .

关 键 词：功能性胃十二指肠病 胃食管反流病 胃气道反流病 

分 类 号：R57[医药卫生—消化系统]