经尿道膀胱肿瘤汽化电切术联合表柔比星治疗非肌层浸润性膀胱癌的临床效果  

Clinical effect of transurethral resection of bladder tumor combined with epirubicin in the treatment of non muscle invasive bladder cancer

作　　者：黄志成[1] 彭栋[1] 陈智林[1] 万沛[1] 朱宇广 陈南辉[1] 

机构地区：[1]广东省梅州市人民医院泌尿外四科,广东梅州514000

出　　处：《中国当代医药》2018年第5期89-91,共3页China Modern Medicine

摘　　要：目的探究经尿道膀胱肿瘤汽化电切术联合表柔比星治疗非肌层浸润性膀胱癌的临床效果。方法选取2014年3月~2016年3月我院收治的40例非肌层浸润性膀胱癌患者随机分配的原则分为观察组(n=20)和对照组(n=20)。两组均给予经尿道膀胱肿瘤汽化电切术进行治疗,对照组加用羟喜树碱或米托蒽醌进行膀胱灌注,观察组加用表柔比星进行膀胱灌注,对比两组患者的导尿管留置时间﹑手术时间﹑不良反应及复发情况。结果两组患者导尿管留置时间﹑手术时间比较,差异无统计学意义(P>0.05);两组患者不良反应发生率比较,差异无统计学意义(χ2=0.28,P=0.60);两组患者复发率比较,差异无统计学意义(χ2=0.20,P=0.66)。结论经尿道膀胱肿瘤汽化电切术联合表柔比星治疗非肌层浸润性膀胱癌的效果确切,复发率低,值得推广。Objective To explore the clinical effect of transurethral bladder tumor vaporizing electrotomy combined with epi in the treatment of non-muscular infiltrating bladder cancer.Methods 40 patients of non-muscle invasive bladder cancer treated in our hospital from March 2014 to March 2016 were divided into observation group （n=20） and control group （n=20）.Two groups were given transurethral electrovaporization of bladder tumor treatment,the control group with hydroxycamptothecin or mitoxantrone for bladder perfusion,observation group with epirubicin for bladder perfusion.The catheter indwelling time,operation time,adverse reactions and recurrence were compared between the two groups.Resuits There was no significant difference in indwelling time and operation time between the two groups （P〉0.05）.There was no significant difference in the incidence of adverse reactions between the two groups （χ2=0.28,P=0.60）.There was no significant difference in recurrence rate between the two groups （χ2=0.20,P=0.66）.Conclusion Transurethral electrovaporization resection of bladder tumor combined with epirubicin in the treatment of non-muscle invasive bladder cancer is effective,the recurrence rate is low, worthy of promotion.

关 键 词：经尿道膀胱肿瘤汽化电切术 表柔比星 非肌层浸润性膀胱癌 

分 类 号：R737.1[医药卫生—肿瘤]