桃红四物汤预防全膝关节置换术后下肢深静脉血栓形成的疗效观察  

Clinical study of oral application of Taohongsiwu decoction in preventing deep venous thrombosis after total knee arthroplasty

作　　者：孙毅[1] 孔乔[2] 

机构地区：[1]滕州市中心人民医院,山东滕州277500 [2]天津中医药大学,天津300193

出　　处：《医药论坛杂志》2017年第12期26-28,共3页Journal of Medical Forum

摘　　要：目的探讨桃红四物汤预防全膝关节置换术后并发下肢深静脉血栓形成的有效性及安全性。方法初次行单侧全膝关节置换术患者54例,随机分为2组,每组27例。观察组予以桃红四物汤口服,每日2次;对照组予以低分子肝素钙5000IU,皮下注射,每日1次,连续注射2周。观察两组患者凝血指标、下肢深静脉血栓形成情况及抗凝费用差异情况。结果手术前后对应时间内两组患者凝血酶原时间及D-二聚体检测结果比较,差异均无统计学意义(P>0.05)。两组间深静脉血栓形成发生率比较,差异无统计学意义(P>0.05)。两组患者抗凝费用相比较,桃红四物汤明显低于低分子肝素钙。结论桃红四物汤口服用于全膝关节置换术后深静脉血栓形成的预防,有效性和安全性与皮下注射低分子肝素钙相当。Objective To observe the safety and effectiveness and of oral application of Taohongsiwu decoction in preventing deep venous thrombosis（ DVT） after total knee arthroplasty（ TKA）. Methods Fifty-four patients underwent unilateral TKA were randomly divided into two groups,27 cases in each group. The patients in the treatment group were treated with oral application of Taohongsiwu decoction,while the patients in control group were treated with low molecular weight heparin calcium injection. All patients in both groups were treated for 2 weeks. The DVT incidence,coagulation indicators,and the cost of anticoagulant were observed. Results There was no statistical difference in PT and D-dimer level between same time points,and there was no statistical significance in the incidence of DVT between the two groups. there was statistical difference in the cost of anticoagulant between the two groups. The treatment group was lower than the control group. Conclusion Oral application of Taohongsiwu decoction is similar to low molecular weight heparin calcium injection in effectiveness in preventing DVT after TKA,but the cost of anticoagulant was lower.

关 键 词：膝关节置换 深静脉血栓 桃红四物汤 

分 类 号：R364.15[医药卫生—病理学]