点状内层脉络膜病变的临床特征与治疗体会  

Clinical features and treatments of punctate inner choroidopathy

作　　者：王向华[1] 赵宏[1] 高延庆[1] 

机构地区：[1]郑州市第二人民医院眼科暨南大学附属郑州医院,郑州450003

出　　处：《医药论坛杂志》2017年第12期76-78,共3页Journal of Medical Forum

摘　　要：目的总结点状内层脉络膜病变(punctate inner choroidopathy,PIC)的临床特征及治疗方法。方法回顾分析12例15眼PIC患者的临床资料。根据检查结果给予观察、曲安奈德球后注射或曲安奈德联合抗VEGF药物玻璃体腔注射等。随访6~36个月。结果单纯PIC 6例9眼,继发CNV 6例6眼,双眼发病3例。所有患者后极部可见多发的深层黄白色病灶,位于RPE层及内层脉络膜。末次随访,最佳矫正视力≤0.1者2眼,0.12~0.5者5眼,>0.5者8眼,2眼视力不提高,视力提高率86.67%。结论 PIC主要发生于合并中高度近视的青年女性,以后极部多发的深层黄白色病灶为主要特征。CNV是常见并发症。根据病灶情况采取相应治疗能够改善患者视功能。Objective To conclude the features and treatments of punctate inner choroidopathy（ PIC） and analyze the prognosis of PIC. Methods The clinical data of 12 PIC patients（ 15 eyes） were review. According to the checking results,some patients were observed and others injected retrobulbar with TA or injected intravitreal with TA and Lucentis respectively. Follow-up time was for 6-36 months. Results Simple PIC developed in 6 cases（ 9 eyes）,choroidal neovascularization（ CNV） developed in 6 cases（ 6 eyes） and 3 patients were bilateral eases. Multiple yellow-white lesions developed in all patients’ posterior pole and located in RPE and deep choroid. At the end of follow-up time,BCVA ≤0. 1 in 2 eyes,0. 12-0. 5 in 5 eyes,〉 0. 5 in 8 eyes. Two eyes of BCVA didn’t improve. BCVA of improvement rate was 86. 67. Conclusion PIC occur in young women with moderate or high myopia primarily. The features of PIC are multiple yellow-white lesions in deep posterior pole. CNV is the most common complication. Different therapy can improve visual function according to different lesions.

关 键 词：点状内层脉络膜病变(PIC) 临床特征 治疗方法 

分 类 号：R773.4[医药卫生—眼科]