基于卵母细胞质量探讨子宫内膜异位症导致不孕的机制  

Exploring the mechanism of infertility caused by endometriosis from the perspective of oocyte quality

作　　者：宋景艳 孙振高[2] 张兴兴[1] 王爱娟[1] 

机构地区：[1]山东中医药大学,济南250011 [2]山东中医药大学附属医院中西医结合生殖与遗传中心,济南250014

出　　处：《中国性科学》2018年第2期115-117,共3页Chinese Journal of Human Sexuality

基　　金：国家自然科学基金项目(81373676;81674018)

摘　　要：伴随着现代文明的不断发展,生育年龄不断推迟,育龄女性中子宫内膜异位症(以下简称内异症)发病率大致为10%~15%,且有逐年上升趋势,故有"现代病"之称。不孕作为内异症的主要临床症状,在辅助生殖技术(ART)助孕人群中占据一席之地,尽管该技术发展迅速,但内异症妇女IVF妊娠率仍旧不高。本文梳理相关领域的文献,旨在通过探讨内异症对卵母细胞质量影响,明确其致不孕的内在机制,寻求改善其助孕结局的思路和方法。With the continuous development of modern civilization,childbearing age has been delayed,and the incidence rate of endometriosis in women of childbearing age is roughly 10 to 15%,with an increasing trend. It is known as ＂ modern disease＂. Infertility as the main clinical symptoms of endometriosis,also takes a large part in the patients seeking assisted reproductive technology（ ART）. Despite the rapid development of the technology,IVF pregnancy rate of women with endometriosis is still not high. The aim of this article is to explore the internal mechanism of infertility caused by endometriosis by examining the effect of endometriosis on oocyte quality,and to seek the ways and methods to improve the outcome of infertility.

关 键 词：子宫内膜异位症 不孕 子宫内膜容受性 卵母细胞质量 

分 类 号：R737.33[医药卫生—肿瘤]