血府逐瘀汤联合帕罗西丁治疗脑卒中后抑郁患者的临床疗效观察  

Clinical Observation of Xuefu Zhuyu Decoction Combined with Paroxetine in Treating Depression after Stroke

作　　者：王琳 

机构地区：[1]解放军第四六三医院康复医学科,辽宁沈阳110042

出　　处：《中国医药指南》2018年第3期7-8,共2页Guide of China Medicine

摘　　要：目的探讨血府逐瘀汤联合帕罗西丁治疗脑卒中后抑郁患者的临床疗效观察。方法选取2015年12月至2016年12月在解放军第四六三医院就诊的脑卒中后抑郁患者60例,随机分为试验组30例和对照组30例,对照组使用帕罗西丁治疗,试验组在对照组的基础上使用血府逐瘀汤治疗,比较两组患者的汉密尔顿抑郁量表(HAMD)。结果试验组与对照组治疗前比较,两组患者没有差异(P>0.05);治疗后比较,试验组各治疗后2周、治疗后6周、治疗后8周的值均优于对照组差异有统计学意义(P<0.05)。结论对脑卒中后抑郁患者使用血府逐瘀汤联合帕罗西丁治疗,可以明显得改善其抑郁状态,值得在临床推广。Objective To investigate the clinical effect of Xuefu Zhuyu Decoction combined with paroxetine in the treatment of post-stroke depression patients. Methods Sixty patients with post-stroke depression who visited the 463 Hospital of PLA from December 2015 to December 2016 were selected and randomly divided into experimental group（30 cases） and control group（30 cases）, and control group（treated with paroxetine） The treatment group was treated with Xuefu Zhuyu Decoction on the basis of the control group, and the Hamilton Depression Rating Scale（HAMD）. Results There was no significant difference between the two groups before and after treatment（P〈0.05）. After treatment, the experimental groups were better than the control group at 2 weeks after treatment, 6 weeks after treatment and 8 weeks after treatment Statistical significance（P〈0.05）. Conclusion The use of Xuefu Zhuyu Decoction combined with paroxetine in patients with post-stroke depression can obviously improve their depression status, which is worthy of clinical promotion.

关 键 词：血府逐瘀汤 帕罗西丁 脑卒中后抑郁 

分 类 号：R743.3[医药卫生—神经病学与精神病学]