食欲素与缺血性脑卒中关系的研究进展  

The Research Progress of Orexins Relationship with Ischemic Stroke

作　　者：熊坤 尹勇[1,2] 袁戎 杨会军[2] 马德阳 

机构地区：[1]昆明医科大学,云南昆明650000 [2]昆明医科大学第四附属医院,云南昆明650021

出　　处：《现代生物医学进展》2017年第36期7173-7175,7095,共4页Progress in Modern Biomedicine

基　　金：国家自然科学基金项目(81460352)

摘　　要：缺血性脑卒中是严重威胁我国人民生命和健康的疾病,具有高发病率、高死亡率和高致残率。食欲素是下丘脑分泌的一种神经肽,包括食欲素A和食欲素B有调节能量平衡、刺激食欲、内分泌、睡眠-苏醒、心血管系统的功能。近年来有研究发现食欲素通过对血糖、血压、炎症以及缺血性脑卒中后抑郁及认知功能的调节,进而影响缺血性脑卒中的预后。本文将对食欲素与缺血性脑卒中的关系做一综述。Ischemic stroke is a serious threat to our country people＇s life and health condition, with a high morbidity, high mortality and morbidity. A neuropeptide orexins are secreted by the hypothalamus, include loss of appetite, A and B, appetite has adjust energy balance, stimulate appetite, endocrine, sleep-wake up, the function of cardiovascular system. In recent years, studies have found that the orexins on blood glucose, blood pressure, inflammation, and after ischemic stroke depression and cognitive function adjustment,will affect the prognosis of ischemic cerebral apoplexy. In this article, we will review on the relationship between the orexins with ischemic stroke.

关 键 词：食欲素 缺血性脑卒中 缺血性脑卒中后抑郁 认知功能 

分 类 号：R743[医药卫生—神经病学与精神病学]