苦味受体在呼吸道中的研究进展  

Research progress of bitterness receptor in respiratory tract

作　　者：余杰情[1] 叶菁[1] 杨勇[2] 叶妤 康雪[1] 罗庆[1] 张剑[1] Yu Jieqing, Ye Jing, Yang Yong, Ye Yu, Kang Xue, Luo Qing, Zhang Jian(Dpartment of Otolaryngology Head and Neck Surgery , the First Affiliated Hospital of Nanchang University, Nanchang 330006, China ; Department of Generalsurgery, Jiangxi Provincial People＇s Hospital Nanchang 330006, China)

机构地区：[1]南昌大学第一附属医院耳鼻咽喉头颈外科,330006 [2]江西省人民医院普外科,南昌330006

出　　处：《国际耳鼻咽喉头颈外科杂志》2018年第2期94-97,共4页International Journal of Otolaryngology-Head and Neck Surgery

基　　金：江西省教育厅青年项目资助（GJJ160247）

摘　　要：苦味的识别作为一种防御机制，能帮助动物避免摄入有毒物质。苦味受体是一类7次跨膜的G蛋白偶联受体，除了在口腔味蕾中表达外，还在其他的组织器官中表达，如胃、胰腺、十二指肠、脑、网膜动脉、心脏、肾脏、睾丸、鼻腔、肺等。本文就苦味受体在呼吸系统的研究进行综述。The recognition of bitterness as a defense mechanism helps animals avoid the intake of toxic substances. The bitter taste receptor is an G protein coupled receptor 7 transmembrane （GPCR）, the bitter taste reeeptor（TAS2R） not only express in oral taste buds, but also expressing in other tissues, such as stomach, pancreas, duodenum, brain, heart, kidney, omental artery, testis, lung, nasal cavity. This article reviews the research on the bitterness receptor in the respiratory system.

关 键 词：味觉 苦味受体 上呼吸道 哮喘 

分 类 号：R332[医药卫生—人体生理学]