超灵敏原子磁力计在生物磁应用中的研究进展  

Progress in Biomagnetic Signal Measurements with Ultra-Sensitive Atomic Magnetometers

作　　者：王晓飞[1,2] 孙献平 赵修超[1] 朱茂华 叶朝辉[1] 周欣 Wang Xiaofei1,2, Sun Xianping1, Zhao Xiuchao1, Zhu Maohua1,2, Ye Chaohui1, Zhou Xin1(1 State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, Wuhan, Hubei 430071, China ; 2University of Chinese Academy of Sciences, Beijing 100049, Chin)

机构地区：[1]中国科学院武汉物理与数学研究所波谱与原子分子物理国家重点实验室,湖北武汉430071 [2]中国科学院大学,北京100049

出　　处：《中国激光》2018年第2期158-170,共13页Chinese Journal of Lasers

基　　金：国家自然科学基金(81227902;81625011);中国科学院科研装备研制项目(2014-2015;2015-2016)

摘　　要：生物体产生的生物磁场信号携带有重要的生物电生理和病理信息,通常用超导量子干涉器件探测这些生物磁。随着原子磁力计发展到飞特斯拉水平,作为一种超灵敏磁场探测器,超灵敏原子磁力计在生物磁的测量和研究中扮演一个非常重要的角色。简要介绍了生物磁场信号来源及其特性,超灵敏原子磁力计的物理机制和分类,以及超灵敏原子磁力计在心磁、脑磁和神经科学等生物磁场测量领域的应用,展望了超灵敏原子磁力计在生物医学领域的应用与发展。Biomagnetic fields produced by organisms carry valuable informations of electrophysiologies and pathologies,which are commonly detected by superconducting quantum interference device.As an ultra-sensitive magnetic field detector with the sensitivity of femtotesla level,the ultra-sensitive atomic magnetometer plays an important role in detection and study of biomagnetism.We introduce the sources and characteristics of biological magnetic field signals,as well as the physical mechanism and classification of ultra-sensitive atomic magnetometers.We also summarize and forecast the applications of ultra-sensitive atomic magnetometers in the field of the biomagnetic field detection,such as magnetocardiography,magnetoencephalography,and neurosciences.

关 键 词：生物光学 原子磁力计 生物磁性 心磁 脑磁 神经冲动 

分 类 号：R318.51[医药卫生—生物医学工程]