炎症因素与脑梗死患者颈动脉粥样硬化的相关性研究  

Correlation between Inflammatory Factors and Carotid Atherosclerosis in Patients with Cerebral Infarction

作　　者：丘为[1] QIU Wei(The People＇s Hospital ofMeizhou, Meizhou 514000, Chin)

机构地区：[1]梅州市人民医院,广东梅州514000

出　　处：《中外医学研究》2018年第8期22-23,共2页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探究炎症因素对脑梗死患者颈动脉粥样硬化的影响。方法:回顾性分析2015年6月-2016年6月笔者所在医院收治的70例脑梗死患者的一般资料,比较颈动脉粥样硬化和颈动脉粥样硬化患者的炎症影响因素,筛选出有统计学意义的变量带入Logistic回归方程进行计算,分析炎症因素对脑梗死患者颈部发生AS的影响。结果:70例脑梗死患者中发生颈动脉粥样硬化者40例,占57.14%;颈动脉粥样硬化与未发生颈动脉粥样硬化的脑梗死患者的单核细胞比例、红细胞沉降率、纤维蛋白原比较,差异均有统计学意义(P<0.05);经多因素Logistic回归分析,单核细胞比例、红细胞沉降率及纤维蛋白原是引起脑梗死患者发生颈动脉粥样硬化的独立危险因素。结论:脑梗死患者中发生颈动脉粥样硬化的概率较高,引起患者发生颈动脉粥样硬化的炎症因素较多,治疗和预防炎症因素,可降低颈动脉粥样硬化的发生。Objective： To analyze the effect of inflammatory factors on carotid atherosclerosis（AS） in patients with cerebral infarction.Method： From June 2015 to June 2016, the clinical data about 70 patients with cerebral infarction treated in our hospital was retrospectively analyzed.The inflammatory factors in patients with carotid atheroselerosis and those without carotid atherosclerosis were compared.The statistically significant variables were screened into logistic regression equation to calculate the inflammatory factors effect of carotid atherosclerosis in patients with cerebral infarction.Result： Forty cases of carotid atherosclerosis occurred in 70 patients with cerebral infarction, accounting for 57.14%.The proportion of mononuclear cells, erythrocyte sedimentation rate and fibrinogen in patients with carotid atheroscterosis and those without carotid atherosclerosis, the differences were statistically significant（P〈0.05）.By multivariate logistic regression analysis, mononuclear cell ratio, erythrocyte sedimentation rate and fibrinogen were independent risk factors of carotid atherosclerosis in patients with cerebral infarction.Conclusion： For cerebral infarction patients, the morbidity of carotid atherosclerosis is relatively high.The multiple inflammatory factors will bring about the genesis of carotid atherosclerosis.The corresponding treatment and prevention measures on the inflammatory factors may further reduce the incidence rate of carotid atherosclerosis.

关 键 词：脑梗死 颈动脉粥样硬化 炎症因素 影响因素 

分 类 号：R743.3[医药卫生—神经病学与精神病学]