大连市气象因素与急性脑梗死发病的相关性分析  

Correlation analysis between meteorological factors and onset of acute cerebral infarction in Dalian

作　　者：林亚楠[1] 郭岩[1] 杨西 陶梦醒 林永忠[2] 马强[3] 孙晓培[1] Lin Yanan , Guo Yan, Yang Xi, Tao Mengxing, Lin Yongzhong, Ma Qiang, Sun Xiaopei(Department of Neurology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, Chin)

机构地区：[1]大连医科大学附属第一医院神经内科,116044 [2]大连医科大学附属第二医院神经内科 [3]大连大学附属中山医院神经内科

出　　处：《中国脑血管病杂志》2018年第3期113-118,共6页Chinese Journal of Cerebrovascular Diseases

摘　　要：目的通过对大连地区急性脑梗死的发病与同期气象因素进行相关性分析,旨在为急性脑梗死的防治提供更多参考依据。方法回顾性分析大连市3所大型综合性三级甲等医院2015年1月1日至12月31日连续收治的3 578例急性脑梗死患者的住院病历资料和大连市同期气象资料。采用描述性分析大连地区急性脑梗死发病的季节规律,采用单项回顾性1∶1配对病例交叉研究设计,分析滞后0~3 d平均气温对急性脑梗死发病的影响;采用Pearson相关性分析当日气象因素对急性脑梗死发病的影响,同时探讨卒中亚型与气象因素的相关性。结果 (1)急性脑梗死的发病呈明显的冬季(12、1、2月)高发,夏季(6、7、8月)低发。(2)滞后分析:气温每降低1℃时,滞后0、1 d急性脑梗死发病的OR值分别为1.034(95%CI:1.012~1.056)、1.025(95%CI:1.008~1.042),差异有统计学意义(均P<0.05),发病当日气温与急性脑梗死的发病相关性最高。(3)急性脑梗死的发病与当日平均气温、日照时数呈负相关(r为-0.392、-0.260,均P<0.01),与日平均气压呈正相关(r为0.403,P<0.01);其中心源性栓塞与气象因素的相关性最高,与日均气温、日均气压、日照时数的相关系数分别为-0.836、0.733、-0.629(均P<0.01)。结论寒冷、气压高的天气可能诱发急性脑梗死发病,尤其是心源性脑梗死。Objective To provide more reference base for the prevention and treatment of acute cerebral infarction through the correlation study between the onset of acute cerebral infarction and meteorological factors during the same period in Dalian area. Methods From January 1,2015 to December 31,2015,the data of hospitalized medical records and meteorological data during the same period in 3578 consecutive patients with acute cerebral infarction admitted to three tertiary hospitals in Dalian were analyzed retrospectively. The seasonal regularity of acute cerebral infarction in Dalian area was analyzed descriptively. A single retrospective 1∶1 matched case-crossover study design was used to analyze the effect of mean air temperature lag 0-3 days on the onset of acute cerebral infarction. Pearson correlation analysis was used to analyze the influence of meteorological factors of the day on the onset of acute cerebral infarction,at the same time,the relationship between stroke subtypes and meteorological factors was investigated.Results （1） The incidence of acute cerebral infarction was higher in winter （December,January,and February） and it was lower in summer（from June to August）.（2） Hysteresis analysis： when the temperature was reduced by 1℃ each time,the OR values of acute cerebral infarction lagging behind 0 and 1 d were 1.034 （95% CI 1.012-1.056） and 1.025（95% CI 1.008-1.042） respectively. There was significant difference（all P〈0.05）. The correlation between the temperature of the day of onset and the onset of acute cerebral infarction was the highest.（3） The onset of cerebral infarction was negatively correlated with the average temperature of the day and hours of sunshine（r=-0.392,-0.260,all P〈0.01）,and it was positively correlated with the daily average air pressure（r=0.403,P〈0.01）. Among them,the correlation of the type of cardiogenic embolism and each meteorological factor was the highest. The correlation coefficients of daily average temperature,daily air press

关 键 词：脑梗死 气象学概念 相关分析 

分 类 号：R743.33[医药卫生—神经病学与精神病学]