彩色多普勒超声联合检测对动脉粥样硬化脑梗死的诊断价值  

Diagnostic value of color Doppler ultrasound in atherosclerotic cerebral infarction

作　　者：李利斌 孙菊光 史江峰 郭春晖 吴冠会[2] LI Libin1 ,SUN Juguang1,SHI Jiangfeng1 ,GUO Chunhui1,WUGuanhui2(1.Department of Neurology, Xuzhou Hospital of Traditional Chinese Medicine, Xuzhou 221000, China;2.Department of Neurology, Suzhou Municipal, Suzhou 215000, Chin)

机构地区：[1]徐州市中医院神经内科,江苏徐州221000 [2]苏州市立医院神经内科,江苏苏州215000

出　　处：《中国实用神经疾病杂志》2018年第6期602-606,共5页Chinese Journal of Practical Nervous Diseases

基　　金：2015年苏州市科技发展项目(SYSD2015106)

摘　　要：目的探讨彩色多普勒超声、踝肱指数及hs-CRP联合检测对动脉粥样硬化脑梗死的诊断价值。方法选择2014-01—2017-01在徐州市中医院就诊的100例脑梗死患者为观察组,同期选择100例健康体检者为对照组。采用免疫比浊增强法检测hs-CRP水平,对所有患者行彩色多普勒超声检查。采用多普勒超声探测仪测量踝肱指数,测量患者上臂肱动脉和足背动脉收缩压,计算踝肱指数。结果观察组动脉狭窄检出率为62.00%,显著高于对照组6.00%,观察组中重度狭窄程度占59.68%,狭窄程度较对照组严重,差异有统计学意义(P<0.05);观察组及对照组动脉粥样硬化部位多为颈总动脉分叉处(P>0.05),观察组斑块性质多为软斑,对照组多为硬斑、混合斑(P<0.05);观察组hs-CRP水平为(7.72±2.03)mg/L,显著高于对照组(2.11±0.21)mg/L;观察组踝肱指数为(0.93±0.14),显著高于对照组(1.18±0.28),差异有统计学意义(P<0.05)。观察组颈总动脉阻力指数检出率明显高于对照组(P<0.05)。结论脑梗死患者动脉粥样硬化斑块多为软斑,且动脉血管狭窄程度较严重,颈总动脉阻力指数较大,hs-CRP水平显著高于非脑梗死患者,彩色多普勒超声和hs-CRP水平联合对动脉粥样硬化脑梗死患者具有较好的诊断性。Objective To evaluate the value of color Doppler ultrasonography,ankle brachial index and hs-CRP in the diagnosis of atheroselerotic cerebral infarction. Methods 100 patients with cerebral infarction treated in our hospital from January 2014 to January 2017 were selected as the obwervation group, and 100 healthy subjects were selected as control group. The level of hs-CRP was detected by immune turbidimetry, and all the subjects were examined by color Doppler ultrasonography. The ankle brachial index was measured by Doppler ultrasonic detector, and the ankle brachial index （ABI） was calculated after measuring the systolic pressure of the upper arm, the brachial artery and the back of the foot,or the posterior tibial artery. Results The observation group artery stenosis detection rate was 62%, significantly higher than 6% in the control group, the observation group, moderate and severe degree of stenosis ratio was 59.68% ,the degree of stenosis was more serious than the control group （P〈0.05）. The observation group was the most common site of atherosclerotic carotid artery bifurcation, compared with the control group （P〉0.05）. Most of the patients in the observation group were soft plaque, while the control group was mostly hard plaque and mixed plaque （P〈0.05）. The hs-CRP level of the observation group was （7.72 ± 2.03） mg/L, which was significantly higher than that of the control group （2.11 ±0.21） mg/L, the ankle brachial index （0.93 ± 0.14） in the observation group was significantly higher than that in the control group （1.18±0.28） （P〈0.05）. The detection rate of resistance index in observation group was significantly higher than that in the control group （P〈0.05）. Conclusion Cerebral infarction patients with atherosclerotic plaque is the soft spot,and the degree of artery stenosis is more serious,the level of hs-CRP was significantly higher than that in patients with cerebral infarction, the resistance index is larger, color Doppler ultrasound combined wit

关 键 词：彩色多普勒超声 踝肱指数 HS-CRP 动脉粥样硬化 脑梗死 诊断 

分 类 号：R743.33[医药卫生—神经病学与精神病学]