广东省部分医院10081例子宫内膜癌流行趋势分析  

Epidemiological features and trends of endometrial cancer:10 081 cases analysis of 62 hospitals in Guangdong province

作　　者：李小毛[1] 叶辉霞[1] 叶敏娟[1] 杨晓辉[1] 郑泽纯[1] Li Xiaomao, Ye Huixia, Ye Minjuan, Yang Xiaohui, Zheng Zechun(Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Sun Yatsen University, Guangzhou 510630, Chin)

机构地区：[1]中山大学附属第三医院妇产科,广州510630

出　　处：《中国医师杂志》2018年第3期367-370,共4页Journal of Chinese Physician

基　　金：广东省自然科学基金(S2012010008640);广东省医学科研基金(B2012118)~~

摘　　要：目的探讨子宫内膜癌(EC)的流行病学特征。方法收集2000年至2010年广东省62家医院确诊的EC病例10 081例,对其临床资料进行统计分析。结果 EC的平均发病年龄(52.8±9.3)岁。≤45岁,>45～60岁及>60岁构成比分别为19.3%,64.2%,16.6%。各年份平均发病年龄差异无统计学意义(F=1.611=0.097);EC发病例数与年份呈正相关(r=0.964,P<0.001);≤30岁(r=0.857,P=0.001),≤35岁(r=0.866,P=0.001),≤40岁(r=0.952,P<0.001),≤45岁(r=0.952,<0.001)患者发病例数与年份呈正相关;各年份≤30岁(X^2=10.390,P=0.407),≤35岁(X^2=11.651,P=0.309),≤40岁(X^2=17.329,P=0.067),≤45岁(X^2=5:154,P=0.881)患者构成比差异无统计学意义。各年份子宫内膜样腺癌患者构成比差异无统计学意义(X^2=16.629,P=0.083)。结论 EC的好发年龄为>45～60岁,其病例数呈逐年增多趋势,但其发病年龄无年轻化趋势。子宫内膜样腺癌为子宫内膜癌的主要组织学类型,其比例无明显升高或降低趋势。Objective To explore the epidemiology characteristics of endometrial cancer （EC）. Methods We retrospectively analyzed 10081 patients diagnosed with EC from 62 hospitals between 2000 and 2010 in Guangdong province. Results The mean age at diagnosis was 52. 8 ± 9. 3. The proportion were 19. 3%, 64. 2%, 16. 6% in patients with ages ≤45, 〉 45 - 60, 〉 60 respectively. From 2000 to 2010, the mean ages at each year were no statistic significance. The number of cases of EC were positively correlated with years（r =0. 964,P 〈0. 001 ）. The number of cases of patients with ≤30 years old （r = 0. 857, P = 0. 001 ）, ≤35 years old （r = 0. 866, P = 0. 001 ）, ≤40 years old （r = 0. 952, P 〈 0. 001 ）, ≤ 45 years old （ r = 0. 952, P 〈 0. 001 ） were positively correlated with years. The ratios of patients with ≤30 years old （ χ^2= 10. 390, P = 0. 407）, ≤ 35 years old （ χ^2 = 11.651, P = 0. 309）, ≤ 40 years old （ χ^2 = 17. 329, P=0. 067） , ≤45 years old （χ^2 =5. 154, P=0. 881） during these eleven years were no statistic significance. The ratios of type I EC at 2000 - 2010 were no statistic significance. Conclusions EC often present in patients aged from 〉 45 - 60 years old. The case number of EC showed an increasing trend. However, the proportion of young patients was stable. The endometroid adenocarcinoma was the main histological type of EC.

关 键 词：子宫内膜肿瘤/流行病学 

分 类 号：R737.33[医药卫生—肿瘤]