平阳霉素联合激素治疗肉芽肿性唇炎的临床疗效评价  

Investigation of the treatment effect of pingyangmycin plus corticosteroids on cheilitis granulomatosa

作　　者：顾玲[1] 黄迪炎[1] 付崇建[1] 王昭领[1] 王栋[1] 杨璐[1] 朱国雄[1] HUANG Di-yan, FU Chong-jian, WANG Zhao-ling, WANG Dong, YANG Lu, ZHU Guo-xiong.(Department of Stomatology, General Hospital of Jinan Military Command. Jinan 250031, Shandong Province, Chin)

机构地区：[1]济南军区总医院口腔科,山东济南250031

出　　处：《中国口腔颌面外科杂志》2018年第2期157-161,共5页China Journal of Oral and Maxillofacial Surgery

基　　金：2015年院长基金面上项目(2015MS12)

摘　　要：目的 :探讨平阳霉素联合激素治疗肉芽肿性唇炎的临床疗效。方法 :选取2008年3月—2016年3月在济南军区总医院口腔科就诊的肉芽肿性唇炎患者78例,行平阳霉素联合激素局部注射治疗,对治疗前、后的病例进行对比,评价治疗效果。结果:肉芽肿性唇炎患者78例,均接受了对患唇的平阳霉素联合地塞米松局部注射治疗,治疗次数1~5次不等,平均3次。73例患者治愈,5例好转。所有病例唇肿胀均得到改善,部分病例面部肿胀亦得到一定程度缓解。结论:平阳霉素联合激素局部注射治疗肉芽肿性唇炎,安全、经济、有效,能改善唇部顽固性肿胀并达到理想的美观效果。PURPOSE： To explore the treatment effect of pingyangmycin plus corticosteroids on cheilitis granulomatosa.METHODS： A retrospective study on 78 patients with cheilitis granulomatosa treated by a new method at our hospital between March 2008 and March 2016 was performed. Pretherapeutic and post-therapeutic medical histories were obtained, and criteria for the success of treatment were evaluated. The outcomes and effects of therapy were analyzed.RESULTS： All patients received intralesional injection of pingyangmycin plus dexamethasone. The number of injections ranged from 1 to 5, with a median of 3 injections. The outcomes were encouraging. Seventy-three cases were cured, 5 cases were improved and none was found ineffective. Swelling of the lips subsided and the skin color returned to normal in all cases. In cases of orofacial involvement, facial asymmetry and orofacial swelling were removed to attain a good esthetic appearance. CONCLUSIONS： The results demonstrated positive responses to the treatment. It is a safe, effective and inexpensive treatment to correct persistent labial swelling and improve lip aesthetics.

关 键 词：肉芽肿性唇炎 梅-罗综合征 平阳霉素 激素 地塞米松 

分 类 号：R781.56[医药卫生—口腔医学]