不同年龄宫颈癌及宫颈癌前病变的临床特征比较  

Comparison of clinical characteristics between cervical cancer and cervical precancerous lesions at different ages

作　　者：罗志明 孙国丽[2] 熊咏珍 黄美群 梁福笑[2] LUO Zhi-ming1, SUN Guo-li2, XIONG Yong-zhen1, HUANG Mei-qun1, LIANG Fu-xiao2(1. Medical Clinic, Guang- dong Medical University, Dongguan 523808, China; 2. Dongguan Maternity and Child Care Hospital, Dongguan 523000, Chin)

机构地区：[1]广东医科大学校门诊部,广东东莞523808 [2]广东省东莞市妇幼保健院,广东东莞523000

出　　处：《广东医科大学学报》2017年第5期508-511,共4页Journal of Guangdong Medical University

基　　金：东莞市科技计划项目(No.2016108101026)

摘　　要：目的探讨不同年龄宫颈癌及宫颈癌前病变的临床特征差异。方法收集10年期间宫颈癌和宫颈上皮内瘤变患者的临床和病理资料,比较两种疾病的临床特征差异。结果共调查452例病例,其中宫颈癌68例,宫颈上皮内瘤变病例384例。宫颈癌病例中阴道不规则出血、接触出血、流液出血、阴道流液发生率均高于癌前病变组(P<0.01),而宫颈上皮内瘤变病例中HPV感染率高于宫颈癌(P<0.01)。宫颈癌病例中阴道不规则出血发生率呈现随年龄增长而上升趋势(P<0.01)。结论宫颈癌病例中阴道出血、流液发生率高于癌前病变病例,且阴道不规则出血随年龄增长而增多。Objective To investigate the difference of clinical characteristics between cervical cancer and cervical precancerous lesions at different ages.Methods Clinical and pathological data of cervical cancer and cervical intraepithelial neoplasia（CIN）were collected during 10 years,and the difference of clinical features was compared between two disorders.Results A total of 452 cases were enrolled,including 68 cervical cancer and 384 CIN cases.Compared with CIN group,irregular vaginal bleeding,contact bleeding,bloody discharge and vaginal discharge were increased（P〈0.01）,while HPV infection rate was decreased（P〈0.01）in cervical cancer group.The irregular vaginal bleeding was incremental with the age in cervical cancer cases（P〈0.01）.Conclusion The incidence rate of irregular vaginal bleeding and discharge is more common in cervical cancer than in CIN.The irregular vaginal bleeding is increased with the age.

关 键 词：宫颈癌 宫颈上皮内瘤变 阴道出血 

分 类 号：R737.33[医药卫生—肿瘤]