2013—2016年贵州省新生儿疾病筛查可疑阳性未召回原因  

Reasons for non-recall suspicious positive cases in neonatal disease screening in Guizhou Province from 2013-2016

作　　者：杨青 牟鸿江[2] 汪俊华 张宏红[2] 王颖[2] YANG Qing1, MU Hong-jiang2, WANG Jun-hua1, ZHANG Hong-hong2, WANG Ying2(1.School of Public Health, Guizhou Medical University, Guiyang Guizhou,550004, China; 2.1nstitute of Maternal and Child Health, Guizhou Center for Disease Control and Prevention, Guiyang Guizhou,550004,Chin)

机构地区：[1]贵州医科大学公共卫生学院,贵州贵阳550004 [2]贵州省疾病预防控制中心妇保所,贵州贵阳550004

出　　处：《职业与健康》2018年第3期336-339,共4页Occupation and Health

基　　金：贵州省卫生计生委科学技术基金(gzwjkj2017-1-088)

摘　　要：目的了解贵州省新生儿疾病筛查可疑阳性召回现况,分析未召回原因,为卫生行政部门提高召回率提供政策建议。方法对2013—2016年贵州省新生儿疾病筛查的可疑阳性相关资料进行回顾性分析,对2016年新生儿疾病筛查可疑阳性新生儿看护人及同等数量已召回新生儿看护人进行配对病例对照分析,对可疑阳性及其未召回情况进行统计描述分析。结果根据贵州省新生儿疾病筛查中心统计数据,贵州省2013—2016年共筛查了1 104 975例,其中先天性甲状腺功能减低症(congenital hypothyroidism,CH)阳性确诊348例,阳性率0.031%,苯丙酮尿症(phenylketonuria,PKU)阳性32例,阳性率0.002%。CH可疑阳性共5 458例,PKU可疑阳性共1 219例,2013—2016年可疑阳性召回率分别是CH为85.07%、68.66%、83.75%和77.52%;PKU为85.04%、72.06%、87.89%和76.41%。趋势χ~2分析显示,近几年可疑阳性未召回率变化差异无统计学意义(P>0.05),但2013—2016年略有上升趋势。召回与未召回两组对比分析显示,可疑阳性新生儿未召回原因主要是可疑阳性新生儿家属主观认知不强,认为筛查没有意义且麻烦占33.96%,初查医院医务人员通知家属直接去上一级医院检查占29.01%,以及有12.96%的家属不知道需要进行复查。结论 2013—2016年贵州省新生儿家疾病筛查可疑阳性未召回主要原因为可疑阳性新生儿家属主观认知不强及初查医院医务人员职责不明。[Objective] To understand the recall status of suspicious positive cases in neonatal disease screening in Guizhou Province, analyze the reasons for the non-recall cases, and provide policy suggestions for health administration department to improve the recall rate. [Methods] The data of suspicious positive cases in neonatal disease screening in Guizhou Province from2013-2016 were retrospectively analyzed. A matched case-control analysis was performed between the caregivers of suspicious positive cases in neonatal disease screening and those of neonatal cases who have been recalled, to carry out the statistical description analysis on suspicious positive cases and non-recall reasons. [Results] According to data from the neonatal disease screening center in Guizhou Province, totally 1 104 975 cases were screened from 2013-2016, and there were 348 cases of congenital hypothyroidism（CH） and 32 cases of phenylketonuria（PKU）, which the positive rate was 0.031% and 0.002%respectively. There were 5 458 suspicious positive cases for CH and 1 219 suspicious positive cases for PKU. During 2013-2016,the suspected positive recall rate of CH was respectively 85.07%, 68.66%, 83.75% and 77.52%, while that of PKU was respectively 85.04%, 72.06%, 87.89% and 76.41%. Trend χ~2 test analysis showed that there was no statistically significant difference in suspected positive recall rate among recent years（P〉0.05）, but the recall rate had upward trend from 2013 to 2016.The matched case-control analysis showed that the non-recall reason was mainly the lower subjective awareness of caregivers of suspicious positive cases. 33.96% of caregivers considered that screening is meaningless and troublesome, the cases that medical workers of the first consultation hospital told their parents directly went to the superior hospital to take the examination accounted for 29.01%, and 12.96% of caregivers did not know the reexamination. [Conclusion] Reasons for non-recall suspicious positive cases in neonatal disease screening in Guizhou

关 键 词：新生儿疾病筛查 可疑阳性 未召回 

分 类 号：R181.39[医药卫生—流行病学]