联合膀胱镜下活检和尿脱落细胞学对膀胱尿路上皮癌诊断的价值  

Diagnosis value of combining biopsy and cytology for patients with urothelial carcinomas of the bladder

作　　者：温宗华[1] 叶见波[1] 韦荣干[1] 黄永塔[1] 韦强[1] Wen Zonghua, et al.(Department of Pathology, The People＇s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, Chin)

机构地区：[1]广西南宁市广西壮族自治区人民医院,530021

出　　处：《齐齐哈尔医学院学报》2017年第24期2865-2867,共3页Journal of Qiqihar Medical University

基　　金：广西壮族自治区卫计委自筹经费课题(Z2014622)

摘　　要：目的探讨联合应用膀胱镜下活检和尿脱落细胞学在膀胱尿路上皮癌诊断中的价值。方法对113例经术后标本确诊为膀胱尿路上皮癌的患者进行回顾性分析。结果膀胱镜下活检诊断阳性97例,阳性率为85.8%(97/113),尿脱落细胞学阳性诊断66例,阳性率为58.4%(66/113),膀胱镜下活检的阳性率明显高于尿脱落细胞学,差异有统计学意义(P<0.01)。联合膀胱镜下活检和尿脱落细胞学,阳性诊断105例,阳性率为92.9%(105/113),阳性率高于单独行膀胱镜下活检或尿脱落细胞学,差异有统计学意义(P<0.01)。结论膀胱镜下活检和尿脱落细胞学检查的联合应用能够提高术前膀胱尿路上皮癌检出率,降低漏诊率,具有较高临床应用价值。Objective To investigate clinical value of urinary cytology in diagnosis of urothelial carcinoma of the bladder. Methods A retrospective analysis was made on 113 cases with urothelial carcinomas of the bladder who were confirmed by radical operation. Results The sensitivity of biopsy was 85.8%（ 97/113）,while that of urinary cytology was 58. 4%（ 66/113）. The sensitivity of biopsy is higher than that of urinary cytology,the difference was statistically significant（ P〈0.01）. When they are combined,the sensitivity was 92.9%（ 105/113）,the sensitivity is higher than that of biopsy or urinary cytology alone,the difference was statistically significant（ P 〈0. 01）. Conclusions Biopsy combined with urinary cytology is helpful to improve detection of urothelial carcinomas of the bladder,decrease the rate of missed diagnosis,which has high clinical value.

关 键 词：膀胱尿路上皮癌 膀胱活检术 尿脱落细胞学检查 诊断 

分 类 号：R737.14[医药卫生—肿瘤]