阿替卡因肾上腺素注射液与利多卡因注射液用于智齿拔除术中的麻醉效果比较  

Comparison of the anesthetic effects of articaine adrenaline injection and lidocaine injection in wisdom tooth extraction

作　　者：胡冠卿 周燕丽 胡建立 Ha Guanqing ,Zhou Yanli ,Hu Jianli.(Department of Pharmacy, the Stomatological Hospital of Haishu District, Ningbo , Zhejiang 315000, China （ Hu GQ ） ; Department of Pharmacy, the Second People＇s Hospital of Hangzhou , Hangzhou , Zhejiang 310015, China （ Zhou YL ） ; Department of Stomatology , Henghe Center Hospital of Cixi , Cixi , Zhejiang 315318, China（ Hu JL ）)

机构地区：[1]宁波市海曙区口腔医院药剂科,浙江省宁波315000 [2]杭州市第二人民医院药剂科,浙江省杭州310015 [3]慈溪市横河中心卫生院口腔科,浙江省慈溪315318

出　　处：《中国基层医药》2018年第8期1034-1037,共4页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的比较阿替卡因肾上腺素注射液与利多卡因注射液在智齿拔除术中麻醉效果。方法选择220例智齿患者作为本次研究的对象，采用随机数字表法分为研究组110例（智齿共132颗，上颌智齿47颗，下颌智齿85颗）和对照组110例（智齿共129颗，上颌智齿51颗，下颌智齿78颗），研究组患者选取阿替卡因肾上腺素注射液麻醉，对照组患者选择盐酸利多卡因注射液麻醉。观察比较两组患者上、下颌智齿麻醉效果、VAS评分及不良反应发生情况。结果研究组上颌智齿麻醉总有效率（100．00％）明显高于对照组（90．20％），差异有统计学意义（χ^2=6．358，P〈0．05）。研究组下颌智齿麻醉总有效率（100．00％）明显高于对照组（92．31％），差异有统计学意义（χ^2=6．788，P〈0．05）。研究组上颌智齿麻醉注射时VAS评分（2．57±0．65）分，显著低于对照组的（2．87±0．63）分，差异有统计学意义（t=2．319，P〈0．05）。对照组出现1例血管所致的局部血肿，研究组患者未出现并发症。结论智齿拔除时，采用阿替卡因肾上腺素注射液麻醉效果显著好于利多卡因注射液的麻醉效果，并未出现并发症，值得临床推广使用。Objective To compare the anesthetic effect of atocaine adrenaline injection and lidocaine injection in wisdom tooth extraction. Methods 220 patients with wisdom teeth were selected as the research subjects. According to the random table method,the patients were randomly divided into research group 110 cases （a total of wisdom teeth 132, maxillary wisdom teeth 47, mandibular wisdom tooth 85 ） and the control group 110 cases （a total of wisdom teeth 129, maxillary wisdom teeth 51, mandibular wisdom tooth 78 ）. The research group received atocaine adrenaline injection, the control group received lidocaine hydroehloride injection. The effects of anesthesia, VAS score and adverse reactions in the two groups were observed. Results The total effective rate of maxillary wisdom tooth anesthesia in the research group（ 100.00% ） was significantly higher than that in the control group （ 90.20% ） , and the difference between the two groups was statistically significant （χ^2 = 6. 358, P 〈 0. 05 ）. The total effective rate of mandibular wisdom tooth anesthesia in the research group（ 100.00% ） was significantly higher than that in the control group（ 92.31% ）, and the difference between the two groups was statistically significant（ χ^2 = 6. 788, P 〈 0.05 ）. The VAS score of maxillary wisdom tooth anesthesia in the research group[ （2.57 ± 0.65 ）pointsJ was significantly lower than that in the control group [ （ 2.87 ± 0. 63 ） points ], and the difference between the two groups was statistically significant（ t = 2.319 ,P 〈 0. 05 ）. In the control group, there was 1 case of hematoma caused by blood vessels, and no complications occurred in the research group. Conclusion The anesthetic effects of articaine adrenaline injection in wisdom tooth extraction is better than lidocaine hydrochloride injection, without any complications, it is worthy of clinical promotion.

关 键 词：拔牙 麻醉 阿替卡因肾上腺素注射液 盐酸利多卡因注射液 

分 类 号：R782.054[医药卫生—口腔医学]