中老年人群水果蔬菜摄入量与血脂水平变化的关系  

The association of fruit and vegetable intake with the changes of serum lipid levels in middle-aged and older Chinese population

作　　者：李潇[1] 李莹[2] 李建新[2] 陈祚[1] 陈纪春[2] 赵连成[1] 武阳丰[3] 顾东风[2] Li Xiao, Li Ying, Li Jianxin, Chen Zuo, Chen Jichun, Zhao Liancheng, Wu Yangfeng, Gu Dongfeng(Division of Prevention and Community Health, Fu Wai Hospital, National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, Chin)

机构地区：[1]中国医学科学院北京协和医学院国家心血管病中心阜外医院社区防治部,北京100037 [2]中国医学科学院北京协和医学院国家心血管病中心阜外医院流行病学研究部,北京100037 [3]北京大学公共卫生学院

出　　处：《中华预防医学杂志》2018年第4期383-388,共6页Chinese Journal of Preventive Medicine

基　　金：国家“十五”科技攻关（2001BA703B01）;国家“十一五”科技支撑计划（2006BA101A01）

摘　　要：目的 了解我国中老年人群水果蔬菜摄入量与血脂水平长期变化的关系。方法 利用中国心血管流行病学多中心协作研究队列人群2004年和2007—2008年调查资料，纳入参加两次调查的不同地区10组城乡社区人群，共4 495名，2004年时调查对象年龄为41~66岁。水果、蔬菜摄入量采用简易食物频数调查问卷获得。计算个体两次调查血清TC、TG、HDL-C、LDL-C变化百分比（ΔTC%、ΔTG%、ΔHDL-C%、ΔLDL-C%）。采用多元线性回归模型分析2004年不同水果及蔬菜摄入组与两次调查间各项血脂指标变化的关系。结果 水果摄入〈250、250~499、≥500 g/周组人数分别占24.0%、21.8%、54.2%；蔬菜摄入〈500、≥500 g/d组人数分别占76.7%、23.3%。以水果摄入量〈250 g/周组为参照，250~499 g/周和≥500 g/周组ΔTC%的β（95%CI）值分别为-1.54（-2.71，-0.37）和-1.77（-2.79，-0.76），ΔLDL-C%的β（95%CI）值分别为-2.43（-4.39，-0.48）和-2.89（-4.59，-1.19）；以蔬菜摄入量〈500 g/d组为参照，≥500 g/d组ΔTC%的β（95%CI）值为-1.01（-1.95，-0.06），ΔLDL-C%的β（95%CI）值为-1.83（-3.41，-0.24）。不同水果、蔬菜摄入量与ΔTG%、ΔHDL-C%无关（P〈0.05）。结论 中老年人群水果、蔬菜摄入量与血清TC和LDL-C水平长期变化均呈负关联，未发现与TG。Objective To investigate the association of fruit and vegetable intake with long-term changes of serum lipid levels in middle-aged Chinese and older Chinese population.Methods The study analyzed the data collected in the 2004 and 2007-2008 cohorts of China Multicenter Collaborative Study of Cardiovascular Epidemiology. Finally, 4 495 participants from 10 groups in various regions of China, who both were followed up in the two cohorts, were included for data analysis. They were aged 41-66 years in 2004. Fruit and vegetable consumption were collected with a simple food frequency questionnaire. The percent changes （Δ%） of serum TC, TG, HDL-C and LDL-C between the two surveys were calculated. Multivariate linear regression models were used to estimate the association of fruit and vegetable intake in 2004 with percentage changes of serum lipid levels during the two surveys.Results The proportions of individuals who consumed fruits 〈250, 250-499 and ≥500 g/week were 24.0%, 21.8% and 54.2%, respectively. The proportions of individuals who consumed vegetables 〈500 and ≥500 g/day were 76.7% and 23.3%, respectively. Compared with fruit intake 〈250 g/week, the regression coefficients （95% CI） of ΔTC% in 250-499 and ≥500 g/week group were -1.54 （-2.71, -0.37） and -1.77 （-2.79, -0.76）. And the regression coefficients （95% CI） of ΔLDL-C% were -2.43 （-4.39, -0.48） and -2.89 （-4.59, -1.19）. Compared with vegetable intake 〈500 g/d, the regression coefficients （95%CI） of ΔTC% and ΔLDL-C% in vegetable intake ≥500 g/d group were -1.01 （-1.95, -0.06） and -1.83 （-3.41, -0.24）. However, fruit and vegetable intake had no relationship with ΔTG% and ΔHDL-C%.Conclusion The consumption of fruit and vegetable was inversely related to long-term changes of TC and LDL-C in middle-aged and older population, but no association was found for changes of TG and HDL-C.

关 键 词：水果 蔬菜 队列研究 血脂变化 

分 类 号：R151[医药卫生—营养与食品卫生学]