同轴微切口超声乳化白内障手术对角膜内皮细胞的影响  

Effect of Coaxial Micro-incision Phacoemulsification Cataract Surgery on the Corneal Endothelial Cells

作　　者：饶玉萍 徐玲娟 游云 崔纪红[4] 游图南 谭向明 RAO Yu-ping1, XU Ling-juan5, YOU Yun2, CUI Ji-hong3, YOU Tu-nan4, TAN Xiang-ming2(1 Department of Ophthalmology, the Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, Enshi, Hubei, 445000, China; 2 Department of Ophthalmology, the Center Hospital, Enshi Hubei, 445000, China; 3 Department of Ophthalmology, the Jianshi People＇s Hospital, Enshi, Hubei, 445000, China; 4 Clinical Laboratory Center, the Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, Enshi, Hubei, 445000, China; 5 Department of Ophthalmology, Tongji Hospital Aftfliated to Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, 430030, Chin)

机构地区：[1]湖北省恩施土家族苗族自治州中心医院眼科,湖北恩施445000 [2]华中科技大学同济医学院附属同济医院眼科,湖北武汉430030 [3]湖北省恩施市中心医院眼科,湖北恩施445000 [4]湖北建始县人民医院眼科,湖北恩施445000 [5]湖北省恩施土家族苗族自治州中心医院检验中心,湖北恩施445000

出　　处：《现代生物医学进展》2018年第5期939-942,共4页Progress in Modern Biomedicine

基　　金：湖北省自然科学基金项目(993137)

摘　　要：目的:分析同轴微切口超声乳化白内障手术对角膜内皮细胞的影响。方法:回顾性分析2015年5月至2016年4月在本院进行治疗的86例白内障患者,以经微切口治疗的43例患者视为观察组,经常规切口治疗的43例患者视为对照组。比较两组患者治疗前、治疗后3天、7天、1个月、3个月的中央角膜厚度、变异系数、六角形细胞比例、角膜内皮细胞密度。结果:治疗前,两组患者中央角膜厚度、变异系数、六角形细胞比例、角膜内皮细胞密度比较差异均无统计学意义(P>0.05),治疗后3天、7天、1个月、3个月,两组患者中央角膜厚度、变异系数、六角形细胞比例、角膜内皮细胞密度较治疗前显著增加(P<0.05),但两组患者之间中央角膜厚度、变异系数、六角形细胞比例、角膜内皮细胞密度比较差异均无统计学意义(P>0.05)。结论:与常规切口治疗白内障相比,微切口治疗白内障对角膜内皮细胞的影响相当,但其能进一步缩小患者手术切口,更有利于患者术后的恢复。Objective： To analyze the effect of coaxial micro-incision phacoemulsification cataract surgery on the corneal endothelial cells. Methods： 86 cases of cataract patients treated in our hospital from May 2015 to April 2016 were selected, 43 patients who were given microsurgical treatment was regarded as the observation group, while 43 patients treated by conventional incision were regarded as the control group. The central corneal thickness, coefficient of variation, hexagonal cell ratio and corneal endothelial cell density were compared between the two groups before treatmet and at 3 d, 7 d, 1 month and 3 months after treatment. Results： Before treatment, there was no significant difference in the central corneal thickness, coefficient of variation, hexagonal cell ratio and corneal endothelial cell density between the two groups （P〉0.05）. At 3 d, 7 d, i month, 3 months after treatment, the central corneal thickness, coefficient of vari- ation, hexagonal cell ratio and corneal endothelial cell density were significantly increased in both groups（P〈0.05）, but no significant difference was found between two groups （P〉0.05）. Conclusion： Compared with conventional incision treatment of cataract, micro-incision cataract had equal effect on the corneal endothelial cells, it could ffu-ther reduce the surgical incision and is more beneficial to the recovery of patients after cataract surgery.

关 键 词：常规切口 微切口 白内障 角膜内皮细胞 

分 类 号：R776.1[医药卫生—眼科] R779.66[医药卫生—临床医学]