绍兴市社区精神分裂症患者复发的影响因素及其防治效果研究  

作　　者：田国强[1] 吴景竹 吴明[1] 

机构地区：[1]浙江省绍兴市第七人民医院,312000

出　　处：《浙江临床医学》2018年第4期727-729,共3页Zhejiang Clinical Medical Journal

摘　　要：目的分析绍兴市社区精神分裂症患者的复发情况及其影响因素，研究采取针对性的防治措施后干预效果。方法2012年6月至2013g-6月期间根据分层抽样的原则，选取本地区、各社区在册社区服药的精神分裂症患者600例，按各辖区县市的总患者数的一定配比抽取。自制调查问卷表，调查患者1年内的复发情况，并对影响患者复发的各因素采用单因素和多因素Logistic回归分析。结果精神分裂症患者干预前的复发率为44％（264／600）。患者的性别、受教育程度、住院时间、服药知识的掌握情况、药物副反应、复诊情况、服药依从性、家庭支持情况、服药情况等因素是社区精神分裂症患者复发的危险因素（P〈0．05）。服药知识的掌握情况、复诊情况、服药依从性和家庭支持情况是影响绍兴市社区精神分裂症患者复发的主要因素（p〈0．05）。实施防治干预措施后600例精神分裂症患者脱落17例，复发154例，复发率（26．42％）明显低于干预前（44．00％），差异有统计学意义（P=0．000）。结论服药知识的掌握情况、复诊情况、服药依从性和家庭支持情况是影响社区精神分裂症患者复发的主要因素，应通过加强患者健康知识教育，督促患者按时复诊并提高服药依从性以及尽可能多争取患者的家庭支持来降低精神分裂症患者的复发率。Objective To analyze the recurrence of schizophrenic patients in Shaoxing City and its influencing factors, to study the effect of intervention after taking preventive measures. Methods According to the principle of stratified sampling, 600 cases （ 600 in 7627 ） of schizophrenic patients who were taken medicine in the community were selected from June 2012 to June 2013. A questionnaire was used, the recurrence of the patients in a year was investigated and the factors influencing the recurrence were analyzed by univariate and multivariate logistic regression analysis. Results In this study, the recurrence rate of before intervention in community schizophrenia patients in Shaoxing City was 44% （264/600） . The factors such as gender, educational level, hospitalization time, the mastery of medication knowledge, drug side effects, referral situation, medication compliance, family support, medication situation and so on were the risk factors of community schizophrenia recurrence （P〈0.05） . The mastery of medication knowledge, referral situation, medication comphance and family support were the main factors influencing the recurrence of community schizophrenia in Shaoxing （ P〈0.05 ） . The recurrence rate （ 26.42% ） was significantly lower than before intervention （ 44.00% ） （ 154 in 583 schizophrenia patients, 17 patient＇s loss ） , the difference was statistically significant （P=0.000） . Conclusion The mastery of medication knowledge, referral situation, medication compliance and family support are the main factors that affect the recurrence of schizophrenic patients. We should strengthen the patient＇s health knowledge education, urge patients to refer patients on time, improve medication compliance and also get as much as possible for the patient＇s family support to reduce the recurrence rate of schizophrenia patients.

关 键 词：精神分裂症 服药依从性 复发因素 LOGISTIC回归 

分 类 号：R749.3[医药卫生—神经病学与精神病学]