急性脑梗死患者椎动脉V4段钙化与脑血流动力学的相关性分析  

作　　者：张宁 计仁杰 刘萍 王安荔[1] 

机构地区：[1]浙江省浦江县人民医院神经内科,322200 [2]浙江大学附属第一医院神经内科,310003

出　　处：《浙江临床医学》2018年第4期747-748,共2页Zhejiang Clinical Medical Journal

摘　　要：目的探讨急性脑梗死患者椎动脉颅内段（V4）钙化的量化指标与脑血流动力学的相关性。方法收集2016年1月至10月住院的急性脑梗死患者的临床资料，根据椎基底动脉cTA检查椎动脉V4段是否钙化分为钙化组和非钙化组，采用经颅多普勒超声检测颅内段椎动脉的峰值流速、平均流速、舒张末期流速、血管搏动指数（PI）等血流动力学参数，比较钙化组与非钙化组椎动脉血流参数的差异。分析V4段钙化与血流动力学参数的相关性。结果钙化组和非钙化组的峰值流速、平均流速、舒张末期流速差异无统计学意义（P〉0．05）；钙化组PI较对照组高，差异具有统计学意义（P〈0．05）。钙化组和非钙化组V4段狭窄情况对比差异无统计学意义（P〉0．05）。Spearman相关性分析显示钙化积分与pI值正相关（r=0．332，P=0．043）。结论急性脑梗死患者椎动脉V锻钙化的发生率高，V4段钙化与血管搏动指数增高相关。Objective To investigate the correlation between intracranial vertebral artery calcification and cerebral hemodynamics in patients with acute cerebral infarction. Methods 138 patients with acute cerebral infarction were divided into calcification group and non-calcification group diagnosed by computer tomography angiography （ CTA ） . Cerebral hemodynamics detected by transcranial doppler （ TCD ） ultrasonography and stenosis incidence were compared between the two groups. The correlation between intracranial vertebral artery calcification and cerebral hemodynamics were analyzed. Results There was no significant difference in peak velocity （ PV ） , diastolic velocity （ DV ） , mean velocity （ MV ） and stenosis between the 2 groups. The pulsatility index （ PI ） of the calcification group was higher than that of non-calcification group. There was no significant difference in stenosis between the 2 groups. PI was positively correlated with calcification （ r=0.332, P=0.043 ） . Conclusion The prevalence ofintracranial vertebral artery calcification in patients with acute cerebral infarction is high. PI is positively correlated with calcification ofintracranial vertebral artery.

关 键 词：急性脑梗死 钙化 脑血流动力学 颅内段椎动脉 

分 类 号：R743.33[医药卫生—神经病学与精神病学]