健脑通络口服液联合尼莫地平治疗老年患者轻中度血管性痴呆的临床疗效  

Effect of Jiannao Tongluo Oral Liquid Combined with Nimodipine in Treatment of Vascular Dementia

作　　者：马瑞[1] 王瑞彤[1] 狄子晖[1] MA Rui, WANG Ruitong, DI Zihui(Department of Neurology, Aerospace Central Hospital, Beijing 100080, Chin)

机构地区：[1]航天中心医院神经内科

出　　处：《辽宁中医杂志》2018年第3期568-570,共3页Liaoning Journal of Traditional Chinese Medicine

摘　　要：目的：观察健脑通络口服液联合尼莫地平治疗老年患者轻中度血管性痴呆（VD）的临床疗效。方法：选取2015年6月—2017年6月期间本院收治的102例VD患者作为研究对象,将所有患者随机分为两组,其中观察组51例（健脑通络口服液联合尼莫地平）,对照组51例（尼莫地平）,比较两组患者的治疗有效率,治疗后的认知功能评价采用简易只能状态量表（MMSE）评分及日常生活能力评定量表（ADL）评分。结果：观察组治疗有效率90.20%（46/52）,对照组为88.24%（45/51）,差异具有统计学意义（Z=12.475,P〈0.05）。两组患者治疗后的MMSE及VDL差异具有统计学意义（P〈0.05）。结论：健脑通络口服液联合尼莫地平治疗血管性痴呆的疗效较为显著。Objective： To study the effect of Jiannao Tongluo Oral liquid combined with nimodipine in treatment of vascular dementia. Methods： From June 2015 to June 2017,102 patients were chosen as study objects,and all of them were divided into 2 groups randomly： 51 patients in study group and 51 patients in control group. The effect,MMSE and ADL were compared between two groups. Results： The effect rate in study group was 90. 20%（ 46/52） and that in control group was 88. 24%（ 45/51）,and the difference was statistically significant（ Z = 12. 475,P〈0. 05）. After treatment,the differences of MMSE and VDL between two groups were statistically significant（ P〈0. 05）. Conclusion： The effect of Jiannao Tongluo Oral Liquid combined with nimodipine in treatment of vascular dementia was reliable.

关 键 词：健脑通络口服液 尼莫地平 血管性痴呆(VD) 

分 类 号：R743[医药卫生—神经病学与精神病学]