山莨菪碱在小儿肠套叠空气整复中的应用改良研究  

Application of anisodamine in modified air repair of intussusception in children

作　　者：张晓华[1] 徐中华[1] ZHANG Xiaohua;XU Zhonghua(Department of Radiology, J iaxing Hospital of Traditional Chinese Medicine, Zhejiang Chinese Medical University ,Jiaxing 314000,China)

机构地区：[1]浙江中医药大学附属嘉兴市中医医院放射科,浙江嘉兴314000

出　　处：《实用放射学杂志》2018年第4期579-581,共3页Journal of Practical Radiology

摘　　要：目的 探讨山莨菪碱（654-2）在小儿肠套叠空气整复中的作用，提高小儿急性肠套叠空气灌肠复位成功率。方法 将临床疑诊并经B超确诊为肠套叠且需做空气灌肠整复的患儿进行筛选，将582例符合纳入标准的患儿按改良操作方法前后分为2组。对照组患儿空气灌肠前未肌注654-2；实验组患儿空气灌肠前肌注654-2。观察和比较2组的首次整复成功率及总成功率，探讨654-2在小儿肠套叠空气整复中的作用。结果 对照组229例首次整复成功，成功率83.9%；17例肌注654-2后二次复位成功；总成功率90.1％。实验组295例首次整复成功，成功率95.5%；3例二次复位成功；总成功率96.4%。实验组首次整复成功率及总成功率均较对照组高。χ2=22.71，P〈0.001，有统计学意义。结论 空气灌肠整复前肌注654-2有助于提高小儿急性肠套叠空气灌肠整复成功率。Objective To investigate the effect of anisodamine on air repair of intussusception in children, to improve the success rate of air enema reduction in children with acute intussusception.Methods Based on the clinical symptoms and ultrasound diagnosis, 582 children who were diagnosed with intussusception and needed air enema reduction were divided into two groups according to the modified method of operation.Children in the control group were not injected 654-2 before the air enema; the experimental group received intramuscular injection of 654-2 before air enema.The success rate and total success rate of the first reduction were observed and compared between the two groups. Results In the control group, 229 cases was successfully repaired, and the success rate was 83.9 ~;17 cases were successfully reset by two times after intramuscular injection of 654-2;the overall success rate was 90.1%.In the experimental group, 295 cases were successfully repaired for the first time,and the success rate was 95.5% ; 3 cases were successfully reset by two times; the overall success rate was 96.4%.The successful rate and the total success rate of the experimental group were higher than those of the control group.;g2 =22.71 ,P^0.001 ,was statistically significant.Conclusion Air enema before intramuscular injection of 654-2 is helpful to improve the success rate of air enema reduction in children with acute intussusception.

关 键 词：山莨菪碱 肠套叠 空气灌肠 

分 类 号：R574.3[医药卫生—消化系统] R472.91[医药卫生—内科学]