肝细胞癌合并门静脉癌栓的治疗进展  

Recent advances on the treatment of hepatocellular carcinoma with portal vein tumor thrombus

作　　者：代柏树 杨振宇[1] 杜锡林[1] 陈安[1] 鲁建国[1] Dai Baishu;Yang Zhenyu;Du Xilin;Chen An;Lu Jianguo(Department of General Surgery, Tangdu Hospital of The Fourth Military Medical University, Shaanxi Xi＇an 710038, China.)

机构地区：[1]第四军医大学唐都医院普通外科,陕西西安710038

出　　处：《现代肿瘤医学》2018年第10期1619-1623,共5页Journal of Modern Oncology

基　　金：陕西省科技统筹创新工程计划项目(编号:2015KTCL03-05)

摘　　要：门静脉癌栓是中晚期肝癌患者最常见的并发症之一,已成为影响肝癌患者术后复发转移和总体生存预后的主要因素之一。近年来,随着医疗技术的不断发展,肝癌精准治疗和多学科协作诊疗等理念不断深入,除传统的手术治疗外,局部消融术、靶向药物治疗、肝动脉栓塞化疗、三维适形放疗等多种手段的联合应用,经过临床应用证实疗效更加显著,肝癌合并门静脉癌栓的综合治疗理念已贯穿始终。本文就肝细胞癌伴门静脉癌栓的最新治疗进展做一综述,以供临床参考。Portal vein tumor thrombus is one of the most common complications of advanced liver cancer.It has become one of the main factors that affect the recurrence and metastasis and the overall survival prognosis of hepatocellular carcinoma patients.In recent years,with the continuous development of medical technology,accurate treatment of liver cancer and multidisciplinary collaboration treatment and other concepts continue to deepen.In addition to traditional surgical treatment,a variety of means of joint application with local ablation,targeted drug therapy,hepatic artery embolization chemotherapy,three-dimensional conformal radiotherapy,have been confirmed more significant after clinical application,and the concept of comprehensive treatment for the patients of liver cancer with portal vein tumor thrombus has been through.This article summarizes the latest advances in hepatocellular carcinoma with portal vein tumor thrombus for clinical reference.

关 键 词：原发性肝癌 门静脉癌栓 索拉非尼 局部消融 

分 类 号：R735.7[医药卫生—肿瘤]